Vertran pills 24mg N60

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22,95 $

Més informació

Active ingredients

Betahistine

Release form

Pills

Composition

Betahistine dihydrochloride 24 mg. Excipients: MCC, mannitol, citric acid monohydrate, colloidal silicon dioxide, talc.

Pharmacological effect

Synthetic analogue of histamine. It acts like histamine mainly on histamine H1 receptors. Causes expansion of precapillaries, in particular, facilitates microcirculation in the maze. In addition, betahistine regulates endolymph pressure in the labyrinth and cochlea, leading to clinical improvement in vertigo of various etiologies. Reduces the frequency and intensity of dizziness, reduces tinnitus, improves hearing in cases of its decline. Increases the tone of the smooth muscles of the bronchi, gastrointestinal tract. May cause increased secretion of gastric juice.

Pharmacokinetics

After oral administration of betahistine, the dihydrochloride is rapidly and almost completely absorbed from the gastrointestinal tract. Plasma protein binding is low. Almost completely excreted in the urine within 24 hours. T1 / 2 - 3-4 hours.

Indications

Meniere's disease. syndromes characterized by dizziness, tinnitus and / or progressive hearing loss, incl. dropsy of the inner ear labyrinth, vestibular and labyrinth disorders (including dizziness, noise and ear pain, headache, nausea, vomiting, hearing loss), vestibular neuritis, labyrinthitis, benign positional dizziness (including after neurosurgical operations) vertebrobasilar insufficiency, post-traumatic encephalopathy, cerebral atherosclerosis (as part of complex therapy).

Contraindications

Pheochromocytoma, gastric ulcer and duodenal ulcer in the acute phase, bronchial asthma, I trimester of pregnancy, hypersensitivity to betahistine.

Precautionary measures

On the part of the digestive system: slight nausea, feeling of heaviness in the epigastrium are possible.

Use during pregnancy and lactation

Not recommended for use in the first trimester of pregnancy and lactation. Caution should be used in the II and III trimesters of pregnancy.

Dosage and administration

Method of application Single dose - 8-16 mg, the multiplicity of reception - 3 times / day. The treatment is carried out for a long time.

Side effects

On the part of the digestive system, slight nausea, feeling of heaviness in the epigastrium are possible. Allergic reactions in some cases - skin rash, itching, urticaria.

Interaction with other drugs

Antihistamines, while taking reduce the effect of betahistine.

special instructions

Caution should be used in patients with gastric ulcer or duodenal ulcer in history, in the II and III trimesters of pregnancy, as well as in children. It must be borne in mind that the desired clinical effect is achieved after several months of treatment. With dyspeptic symptoms, betahistine is recommended to be taken during or after a meal.

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