Belosalic lotion with a spray nozzle 100ml
Condition: New product
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Active ingredients
Betamethasone + Salicylic Acid
Release form
Spray
Composition
Betamethasone dipropionate 640 mcg, which corresponds to the content of betamethasone 500 mcg, salicylic acid 20 mg. Auxiliary substances: disodium edetate - 0.3 mg, hypromellose 4000 cPz - 5 mg, sodium hydroxide - 5 mg, isopropanol - 392 mg, water - 577.06 mg.
Pharmacological effect
Drug for external use. Belosalic; The lotion has anti-inflammatory, antipruritic, anti-edematous, anti-allergic, anti-proliferative, immunosuppressive, keratolytic, anti-microbial, anti-fungal effect. Betamethasone dipropionate is a synthetic GCS that has an anti-inflammatory, anti-allergic, anti-tonic and vessel and vessel and vessel and vessel and vessel and vessel and vessel that is anti-inflammatory, anti-inflammatory, anti-inflammatory, anti-inflammatory. When applied to the surface of the skin narrows blood vessels, relieves itching, reduces the release of inflammatory mediators (from eosinophils and mast cells), interleukins 1 and 2, gamma interferon (from lymphocytes and macrophages), inhibits the activity of hyaluronidase and reduces the permeability of the vascular wall. Interacts with specific receptors in the cytoplasm of the cell, stimulates the synthesis of mRNA, inducing the formation of proteins, including lipocortin, mediating cellular effects. Lipokortin inhibits phospholipase A2 block the release of arachidonic acid biosynthesis endoperekisey, prostaglandins, leukotrienes (contributing to the development of inflammation, allergy and other pathologic processes) .Salitsilovaya acid due keratolytic action clears the lesion portions of the flakes, betamethasone promotes the penetration into the skin, maintains the acidic environment of the skin , preventing the development of bacterial and fungal infections.
Pharmacokinetics
Data on the pharmacokinetics of the drug Belosalic; lotion not provided.
Indications
Subacute and chronic dermatosis, sensitive to GCS therapy, and accompanied by hyperkeratosis and desquamation: - psoriasis; - seborrhea; - seborrheic dermatitis (scalp); - asbestos lichen; - neurodermatitis; - lichen planus with localization on the hairy part of the head - eczema; - dyshidrosis of the skin; - ichthyosis.
Contraindications
- tuberculosis of the skin; - skin manifestations of syphilis; - chicken pox; - viral infections of the skin; - skin post-vaccination reactions; - open wounds; - trophic ulcers; - rosacea; - acne vulgaris; - children up to 6 months; - hypersensitivity to betamethasone , salicylic acid or any of the auxiliary components of the drug.
Precautionary measures
Use in childrenIt is contraindicated in children up to 6 months. The use of the drug Belosalic in children should be as short as possible while observing strict precautions, because in children, there is a danger of systemic absorption in proportion to a larger number of active components due to the predominance of skin area over body weight and insufficient maturity of the epidermis. Do not use the drug in children under bandages and, especially under plasticized diapers, which may increase the risk of developing adverse events.
Use during pregnancy and lactation
Use of the drug Belosalic; lotion in pregnant women is allowed in cases where the intended benefit to the mother exceeds the risk to the fetus. In such cases, the use of the drug should be short and limited to small areas of the skin. During breastfeeding, the use of the drug Belosalic; Lotion is possible under strict indications, but at the same time the drug should not be applied on the skin of the mammary gland before feeding.
Dosage and administration
The drug is intended for external use. A few drops of the solution for external use are evenly distributed over the surface of the skin, slightly rubbing. The frequency of use is 2 times / day, in mild cases a single use is sufficient. The duration of a continuous course of treatment is usually limited to 3-4 weeks. If necessary, a longer course of therapy is recommended to use the drug less often, for example, every other day. The drug can be administered with caution to children from 6 months and for the shortest possible time.
Side effects
Side effects are usually reversible and have a mild nature. On the skin side: hypersensitivity reactions (itching, burning, hyperemia), acne-like changes, hypopigmentation, striae, atrophy of the skin, hypertrichosis, secondary infections of the skin are possible. and when applied to large areas of the skin: telangiectasia, systemic manifestations of side effects of GCS or salicylates. When a hypersensitivity reaction or side reactions develop, the drug should be withdrawn and to marry a doctor.
Overdose
Symptoms: manifestation of systemic side effects. Treatment: recommended drug withdrawal and symptomatic therapy.
Interaction with other drugs
No clinically significant interaction with other drugs has been noted. Simultaneous use of cosmetic and dermatological preparations for external use containing ethanol or medical soap with a pronounced drying effect may cause skin irritation.
special instructions
The drug is intended for external use only. Avoid contact with the eyes and mucous membranes, as well as the use of the drug in the anogenital area. It is not recommended to use the drug under an occlusive dressing, except when necessary. additional use of an antibacterial or antifungal agent is necessary. The preparation Belosalic; Lotion in the form of a solution for external use is particularly suitable for use on the skin of the scalp. The solution is easily distributed over the surface of the skin, does not stick or dry hair, leaves no visible marks, has a cooling effect on the skin. Impact on the ability to drive vehicles and control mechanisms of the adverse effects of the drug Belosalic; Lotion on the ability to drive vehicles and machinery is not available.