Berocca plus pill-bearing N10 (15)
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Description
Flat-orange pills from pale orange to light orange, interspersed with a darker and lighter color, dissolve in water with the release of bubbles, forming a solution with the smell of orange.
Active ingredients
Multivitamins + Minerals
The brand
Berocca Plus
Release form
Pills
Composition
1 tablet contains the Active substances: Vitamin B1 (thiamine hydrochloride) 15 mg, Vitamin B2 (riboflavin) 15 mg, Vitamin B6 (pyridoxine hydrochloride) 10 mg, Vitamin B12 (cyanocobalamin) 0.01 mg, Vitamin B3 (nicotinamide) 50 mg, Vitamin B5 (pantothenic acid) 23 mg, Biotin 0.15 mg, Folic acid 0.4 mg, Vitamin C (ascorbic acid) 500 mg, Calcium (in the form of calcium carbonate and calcium pantothenate) 100 mg, Magnesium (in the form of magnesium carbonate heavy and magnesium sulfate dihydrate) 100 mg, Zinc (in the form of zinc trihydrate) 10 mg, Excipients: citric acid Argodic 1700 mg, sodium bicarbonate 840 mg, sodium carbonate anhydrous 60 mg, sodium chloride 40 mg, acesulfame potassium 20 mg, aspartame 25 mg, beet red (E162) 30 mg, beta carotene (E160a) 40 mg, orange flavoring 100 mg , polysorbate 60 0.9 mg, mannitol 16.848 mg, isomalt 265.531 mg, sorbitol 155.3027 mg. In the form of thiamine monophosphoric acid chloride ester 18.54 mg. In the form of riboflavin sodium phosphate 20.51 mg. In the form of cyanocobalamin 0.1% 10.0 mg. In the form of calcium pantothenate 25 mg. In the form of granulated calcium carbonate (calcium carbonate and maltodextrin) 97.69 mg and calcium pantothenate 2.31 mg. In the form of magnesium carbonate granulated (magnesium carbonate is heavy and pregelatinized corn starch) 49.0 mg and magnesium sulfate dihydrate 51.0 mg. In the form of zinc citrate trihydrate.
Pharmacological effect
The combined drug, the pharmacological action of which is due to its complex of vitamins and trace elements. B vitamins are involved in many metabolic reactions, including the synthesis of neurotransmitters. Vitamin C (ascorbic acid) is a biological antioxidant and plays an important role in the inactivation of free radicals, increases the absorption of iron in the small intestine, affects the metabolism of folic acid and the function of leukocytes. Stimulates the formation of connective tissue, bone tissue, normalizes capillary permeability. Calcium is involved in many physiological processes, enzyme systems and the transmission of nerve impulses in combination with magnesium and vitamin B6.Magnesium is involved in various reactions, including protein synthesis, the metabolism of fatty acids, the oxidation of sugars. Zinc as a catalyst activates more than 200 enzymes and is a component of many proteins, hormones, neuropeptides, hormonal receptors, and also directly participates in the synthesis of coenzymes derived from vitamin B6. The content of vitamins in the drug Berocca Plus is selected for therapeutic use and is used in conditions accompanied by a deficiency or increase in the need for vitamins (increased physical exertion, during prolonged nervous overstrain and stress; in case of inadequate and unbalanced nutrition (restricting diets); in elderly people in chronic alcoholism, nicotine addiction (in smokers), as well as the use of oral contraceptives in women. Water-soluble vitamins do not accumulate in the body, therefore, in conditions accompanied by an increased need for vitamins and minerals, the amount of vitamins from food may be insufficient.
Indications
Deficiency or condition, accompanied by an increased need for vitamins of group B, vitamin C and zinc.
Contraindications
Hypersensitivity to the components of the drug, hypercalcemia, hypermagnemia, urolithiasis (nephrolithiasis, urolithiasis), hemochromatosis, hyperoxaluria, renal failure, deficiency of glucose-6-phosphate dehydrogenase, fructose intolerance, children under 15 years of age.
Precautionary measures
In case of atrophic gastritis, intestinal and pancreatic diseases, vitamin B12 absorption deficiency syndrome or congenital deficiency of the internal factor of Castle.
Use during pregnancy and lactation
When using the drug Berocca Plus in the recommended dosage data on the negative impact of the drug on the course of pregnancy or the health of the child was not detected. However, during pregnancy, the drug should be taken strictly for medical reasons. Vitamins and minerals contained in the preparation of Berocca Plus, penetrate into breast milk. There are no data on the safety of the drug when it is used during lactation.
Dosage and administration
The drug is taken orally, pre-dissolving the tablet in a glass of water. Adults and children from 15 years: 1 tablet per day.Do not exceed the recommended daily dose of the drug. The recommended duration of treatment is 30 days. Repeated courses on the recommendation of a doctor.
Side effects
Allergic reactions: rarely (<1/10000) urticaria, rash, laryngeal edema, anaphylactic shock. Digestive system: transient gastrointestinal disorders are possible. Blood and hematopoietic system: Ascorbic acid can cause hemolytic anemia in patients with a deficiency of glucose-6-phosphate dehydrogenase. Nervous system: headache, dizziness, insomnia, excitability.
Overdose
No cases of overdose have been reported. Overdose symptoms may include gastrointestinal disorders, such as diarrhea and a feeling of discomfort in the stomach. Excessive intake of vitamin B6 (more than 20 pills per day and for several months) can lead to symptoms of neuropathy. In case of overdose, stop taking the drug and consult a doctor.
Interaction with other drugs
Vitamin B6 (pyridoxine), in a dose exceeding 5 mg, can neutralize the effect of levodopa in patients with parkinsonism. However, such antagonism is not observed if levodopa is used in combination with a decarboxylase inhibitor (for example, benserazide, cardbidopa). Thiosemicarbazone and 5-fluorouracil neutralize the effects of vitamin B1. Antacids inhibit the resorption of vitamin B1. Neomycin, aminosalicylic acid and H2 blockers reduce the absorption of vitamin B12. Aspirin reduces the absorption of ascorbic acid by about a third. Oral contraceptives can reduce serum levels of vitamin B12, folic acid, pyridoxine, ascorbic acid. Some patients who take deferoxamine and vitamin C daily at a dose of 500 mg may experience transient dysfunction of the left ventricle.
special instructions
Vitamin C can affect urine glucose test results, although it does not affect blood sugar levels. Reception of vitamin C should be stopped for several days before carrying out such tests. Possible staining of urine in the yellow color, which has no clinical significance and is explained by the presence of riboflavin in the preparation. The drug does not contain fat-soluble vitamins.One tablet of the drug contains the maximum daily dose of vitamin B6 (pyridoxine), so do not exceed the recommended dose of the drug. One tablet contains 12.5% of the recommended daily intake of calcium and 33.3% of the recommended daily intake of magnesium. However, for the treatment of calcium and magnesium deficiency, taking only the drug Berocca Plus is insufficient. One tablet contains 272 mg of sodium, so patients on a low salt diet are advised to take Berocca Plus in the form of coated pills. Information for diabetics. One tablet of the drug contains 276 mg of mannitol, which corresponds to 0.028 bread unit (EC), and an energy value of 0.66 kcal, so the drug can be taken in patients with diabetes. If you are intolerant of some sugars, before taking the drug, you should consult with your doctor. Patients taking other medications should consult with their physician before starting to take the drug Berocca Plus. Influence on ability to drive a car or moving machinery: No effect.
Storage conditions
At a temperature not higher than 25 ° С, in tightly closed package. Keep out of the reach of children.