1 capsule contains: 0.25g clarithromycin.
Bacterial infections caused by susceptible microorganisms: infections of the upper respiratory tract (laryngitis, pharyngitis, tonsillitis, sinusitis), lower respiratory tract (bronchitis, pneumonia, atypical pneumonia), skin and soft tissues (folliculitis, furunculosis, impetigo, wound infection), otitis. peptic ulcer and 12 duodenal ulcer, mycobacteriosis, chlamydia.
Hypersensitivity, porphyria, pregnancy (I trimester), lactation, the simultaneous reception of cisapride, pimozide, terfenadina. C caution. Renal and / or liver failure.
Dosage and administration
Inside, adults and children over 12 years old - 250-500 mg 2 times a day. The duration of treatment is 6-14 days. In case of severe infections or in case of difficulty in oral administration, it is prescribed in the form of intravenous injection in a dose of 500 mg / day for 2-5 days, with further transfer to oral administration of 500 mg / day. The total duration of treatment is 10 days. When treating infections caused by Mycobacterium avium, sinusitis, as well as severe infections (including those caused by Haemophilus influenzae), it is prescribed Inside, 0.5-1 g 2 times a day (maximum 2 g). The duration of treatment is 6 months or more. Children are given as a suspension in a dose of 7.5 mg / kg every 12 hours. The maximum daily dose is 500 mg. The duration of treatment is 7-10 days. In patients with chronic renal failure (CK less than 30 ml / min or serum creatinine concentration more than 3.3 mg / 100 ml) - 250 mg / day (once), for severe infections - 250 mg 2 times a day. The maximum duration of treatment in patients of this group is 14 days.
On the part of the nervous system, headache, dizziness, anxiety, fear, insomnia, nightmares. rarely, disorientation, hallucinations, psychosis, depersonalization, confusion. On the part of the digestive system, nausea, vomiting, gastralgia, diarrhea, stomatitis, glossitis, increased activity of hepatic transaminases, cholestatic jaundice, rarely pseudomembranous enterocolitis. change in taste (dysgeusia). in rare cases - loss of hearing that passes after the abolition preparata.So side of hematopoiesis and hemostasis system rarely - thrombocytopenia (unusual bleeding, hemorrhage) .Allergicheskie reaction skin rash, pruritus, malignant exudative erythema (Stevens-Johnson syndrome), anaphylactoid reaktsii.Prochie development of microbial resistance. Overdose.Symptoms of gastrointestinal dysfunction, headache, confusion. Treatment of gastric lavage, symptomatic therapy.