Maxicold ENT spray for local use 40 ml
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Active ingredients
Paracetamol + Phenylephrine + Ascorbic Acid
Release form
Spray
Composition
Hexetidine 200 mg Auxiliary substances: sodium saccharinate dihydrate - 40 mg, citric acid monohydrate - 70 mg, sodium hydroxide (sodium hydroxide) - 19 mg, glycerol (glycerin) - 17000 mg, ethanol (ethyl alcohol, rectified) - 4000 mg, lauromacrogol (macrogol lauryl ether) - 1500 mg, cineol (eucalyptol) - 20 mg, levomenthol (L-menthol) - 20 mg, peppermint oil - 10 mg, purified water - up to 100 ml.
Pharmacological effect
Antiseptic preparation for local use. It has antimicrobial, antifungal, analgesic, coating and deodorizing action. Anti-microbial effect of the drug Maxicold; ENT is associated with the suppression of oxidative metabolic reactions of bacteria (hexatidine - thiamine antagonist). The drug has a broad spectrum of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida, but the drug Maxicold; ENT may also have an effect in the treatment of infections caused by, for example, Pseudomonas aeruginosa or Proteus spp. At a concentration of 100 mg / ml, the drug inhibits most strains of bacteria. The development of sustainability was not observed. Maxicold; ENT has a weak anesthetic effect on the mucous membrane.
Pharmacokinetics
After a single application, the local effect of hexatidine lasts 10-12 hours. The preparation is practically not absorbed from the surface of the mucous membranes and does not have a systemic effect. After a single application of the active substance, traces of it are found on the mucous membrane of the gums for 65 hours. In the plaques of the teeth, active concentrations persist for 10-14 hours after application.
Indications
- infectious and inflammatory diseases of the oral cavity and pharynx (tonsillitis, including Plauta-Vincent's sore throat, pharyngitis, stomatitis, aphthous mouth ulcers, glossitis, periodontitis, gingivitis, periodontal disease, periodontal disease, alveolitis), gingival bleeding; - with ORZ - as an aid, as part of complex therapy; - fungal infections of the oral cavity, pharynx and larynx (thrush); - injuries and surgical interventions in the oral cavity, pharynx and larynx (both before and after), in t. hprevention of infection of the alveoli after extraction of the tooth; - as a means of oral hygiene to eliminate unpleasant odor (deodorizing effect); - prevention of superinfection with decaying tumors of the oral cavity and larynx.
Contraindications
- atrophic pharyngitis; - children's age up to 3 years; - hypersensitivity to the drug components.
Precautionary measures
During treatment, psoriasis may worsen. During pheochromocytoma, propranolol can only be used after taking an alpha blocker. After a long course of treatment, propranolol should be discontinued gradually, under the supervision of a physician. during anesthesia, you must stop taking propranolol or find a remedy for anesthesia with minimal negative inotropic effects. The impact on the ability to drive vehicles and control mechanisms of patients whose activities require increased attention, the question of the use of propranolol on an outpatient basis should be addressed only after evaluating the individual response of the patient.
Use during pregnancy and lactation
There are no reports of any adverse effects of hexatidine during pregnancy and lactation. Before prescribing the drug to pregnant or lactating women, the doctor should carefully weigh the benefits of treatment for the mother and the possible risks to the fetus and baby, given the lack of sufficient data on the penetration of the drug through the placenta and into breast milk.
Dosage and administration
Apply topically, after a meal or in the intervals between meals. With the help of the spray, the affected areas in the oral cavity and pharynx are treated. The frequency of use for adults and children over 3 years old - 2-3 times / day. If necessary, more frequent use of the drug. The course of treatment is 5-7 days. To properly use the drug, you must perform the following steps: 1. Remove the cap from the cylinder, install the sprayer in the corresponding hole in the upper part of the cylinder.2. When using for the first time, it is necessary to first make a few short presses on the sprayer (in order to ensure uniform spraying of the contents of the cylinder) .3.Enter the required amount of the drug in the oral cavity, pressing all the way to the sprayer 3-4 times. During the administration of the drug should hold your breath. After use, remove the nebulizer, rinse it in running water and dry at room temperature out of the reach of children. The nebulizer should be stored in the package along with the preparation. During insertion, the balloon should be held vertically.
Side effects
Local reactions: allergic reactions, burning of the mucous membrane of the oral cavity. When accidentally swallowed: nausea. With prolonged use: a violation of taste.
Overdose
Hexetidine in the indicated dosage is non-toxic. Ingestion of large quantities of the drug leads to vomiting, therefore, significant absorption is not expected. No cases of ethanol poisoning have been described during overdose. Acute alcohol poisoning is very unlikely, but it is theoretically possible if a large child is swallowed a large dose of the drug. In any cases of overdose, you should immediately consult a doctor. Symptomatic treatment: taking enterosorbents (activated carbon), gastric lavage, and abundant drinking. Gastric lavage is necessary within 2 hours after ingesting an excess dose.
Interaction with other drugs
Data on drug interactions of the drug Maxicold; Lor no.
special instructions
Children can use the drug from an age when they do not resist a foreign object (spray) in the mouth when applying a spray and are able to hold their breath when the drug is injected. The spray should not be inhaled; Contact with the drug should be avoided. After applying the spray, the applicator should be rinsed with warm water. It should be borne in mind that the spray contains ethanol - 24-48 mg per daily dose. It should be taken into account that the balloon is under pressure. Do not burn, pierce or open the cylinder, even if it is empty. Effect on the ability to drive vehicles and control mechanisms In the absence of a general reaction to the drug, the performance of potentially hazardous activities that require special attention and quick reactions (including driving) not contraindicated.