Proproten 100 lozenges 20 pcs
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Active ingredients
Antibodies to the brain-specific protein S-100
Release form
Pills
Composition
In 1 tablet: affinity purified antibodies to the brain-specific protein S-100 3 mg; Additional substances: lactose, microcrystalline cellulose, Ca stearate and / or Mg stearate, aerosil.
Pharmacological effect
The drug modifies the functional activity of the protein S-100, carrying out the conjugation of information and metabolic processes in the brain. Sensitizes the neuronal membrane, modulates the synaptic plasticity of neurons. It has a modifying effect on the functional state of the brain structures involved in the formation of alcohol dependence: the hypothalamus, hippocampus .; When alcohol dependence has a normalizing effect on the system of positive emotional reinforcement, which leads to a decrease in the frequency of self-stimulation of the lateral hypothalamus. Reduces the packet activity of the hippocampal neurons; reduces the number of circulating immunocomplexes in the peripheral blood, which correlates with a decrease in ethanol consumption. Contributes to the strengthening of the inhibitory effects of GABA in the central nervous system. It was established experimentally that the drug restores neurotransmitter balance and conditioned reflex activity. Increases the resistance of the brain to hypoxia and toxic effects.
Indications
Monotherapy of mild to moderate alcohol withdrawal syndrome .; It has anti-alcohol effect, reduces craving for alcohol and reduces the likelihood of relapse .; The drug relieves both psychopathological disorders (anxiety, mental tension, insomnia, irritability, anxiety, low mood, intense craving for alcohol), and somatovegetative disorders (weakness, sweating, headache, tremor, tachycardia, digestive disorders) of alcoholic hangover syndrome.
Dosage and administration
It is recommended to take the drug 15-20 minutes before a meal, not to swallow a pill, but to keep it in the mouth until completely dissolved .; In acute abstinence syndrome, 1 tablet, every half hour, for the first 2 hours, then 1 tablet every hour, for 8 hours. When a break for sleep, after waking up, take the drug according to the previous scheme .; After eliminating the symptoms and improving the general condition, they switch to the drug every 2-3 hours (or 4-6 pills per day) for 3 days.Then they switch to a long-term (up to 3 months) intake of the drug, 1-2 pills per day .; If, while taking Proproten within 12 hours, there is no improvement in the condition, it is necessary to add traditional detoxification and symptomatic therapy.
Side effects
Possible individual hypersensitivity reactions to the drug.