Viferon gel for local approx. 36000me ml 10ml (12gr)
Condition: New product
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Active ingredients
Interferon alfa-2
Release form
Gel
Composition
In 1 gram of gel: Interferon alpha-2b human recombinant 36,000 IU. Adjuvants: α-tocopherol acetate - 55 mg, benzoic acid - 1.28 mg, sodium tetraborate decahydrate - 1.8 mg, methionine - 1.2 mg, citric acid monohydrate - 1 mg , sodium chloride - 4 mg, albumin serum human 10% - 20 mg, glycerol (distilled glycerin) - 20 mg, carmellose sodium - 20 mg, ethanol 95% - 55 mg, purified water - up to 1 g
Pharmacological effect
Interferon alpha-2b human recombinant has immunomodulatory, antiviral and anti-proliferative properties. Suppresses the replication of RNA and DNA viruses. The immunomodulating properties of interferon, such as enhancing the phagocytic activity of macrophages, increasing the specific cytotoxicity of lymphocytes to target cells, determine its mediated antibacterial activity. allows you to increase the effectiveness of the body's own immune response to pathogens. rat has a strong local immunomodulatory action and increases locally produced secretory IgA class antibodies that prevent locking and multiplication of pathogenic microorganisms in the mucous membranes, which provides a prophylactic effect of a preparation for the prophylaxis of viral or other zabolevaniy.Gelevaya base provides a prolonged action of the drug. Antioxidants that are part of the dosage form - alpha-tocopherol acetate, citric and benzoic acids, have anti-inflammatory, membrane-stabilizing, regenerating properties, as well as contribute to the preservation of the biological activity of human interferon alpha-2b recombinant.
Pharmacokinetics
Interferon alpha-2b human recombinant has pronounced immunomodulatory, antiviral, antiproliferative properties, inhibits the replication of RNA and DNA-containing viruses.The complex composition of drugs (ointment, suppositories, gel) causes a number of additional additional effects: in the presence of antioxidants (tocopherol acetate and / or ascorbic acid), the specific antiviral activity of interferon human recombinant alpha 2b increases, its immunomodulating effect on T and B lymphocytes increases , the level of class A secretory immunoglobulins rises, the level of immunoglobulin E is normalized, the functioning of the endogenous interferon alfa-2b system is restored. Ascorbic acid and alpha-tocopherol acetate, being highly active antioxidants, have anti-inflammatory, membrane-stabilizing, and regenerating properties. The use of the drug VIFERON as part of complex therapy allows to reduce therapeutic doses of antibacterial and hormonal drugs, as well as reduce the toxic effects of this therapy. It was established that when using the drug VIFERON, there are no side effects that occur when parenteral administration of interferon alfa-2b preparations, no antibodies are formed that neutralize the antiviral activity of interferon alpha 2b.
Indications
In the complex therapy of SARS, incl. influenza, frequent and prolonged ARVI, including complicated by bacterial infection; prevention of acute respiratory viral infections, including influenza; as part of complex therapy for recurrent stenosing laryngotracheobronchitis; prevention of recurrent stenotic laryngotracheobronchitis; urogenital herpes infection; - in the complex treatment of herpetic cervicitis.
Contraindications
Hypersensitivity to the drug.
Precautionary measures
Possible use in children according to indications.
Use during pregnancy and lactation
Pregnancy and lactation (breastfeeding) are not a contraindication to the use of the drug due to the very low absorption of the components. During lactation, do not apply to the nipple area and areola.
Dosage and administration
The drug is used externally and locally. As part of complex treatment of ARVI, including influenza, long-term and frequent ARVI, includingcomplicated by bacterial infection: a strip of gel no longer than 0.5 cm in length is applied to the previously dried surface of the nasal mucosa and / or on the surface of the tonsils 3-5 times / day using a spatula or cotton wool / cotton swab. The course of treatment is 5 days, if necessary, the course can be extended. Prevention of SARS, including flu: during the period of rising incidence, a strip of gel no longer than 0.5 cm in length is applied on the previously dried surface of the nasal mucosa and / or on the surface of the tonsils 2 times / day. for 2-4 weeks. As part of complex therapy for recurrent stenosing laryngotracheobronchitis: a strip of gel no longer than 0.5 cm in length is applied to the surface of the tonsils using a spatula or cotton swab / cotton swab in an acute peri de disease 5 times / day, for 5-7 days, then 3 times / day for the next 3 weeks. Prevention of recurrent stenosing laryngotracheobronchitis: a strip of gel no longer than 0.5 cm is applied to the surface of the tonsils with a spatula or cotton wool / cotton wool sticks 2 times / day for 3-4 weeks, courses are repeated 2 times a year. As part of complex therapy for acute and chronic recurrent herpetic infection (when the first signs of the disease appear or during precursors): a strip of gel no longer than 0.5 cm in length worn with a spatula or cotton swab / cotton swab on a pre-dried affected surface 3-5 times / day for 5-6 days, if necessary, the duration of the course is increased until the clinical manifestations disappear. As part of complex therapy of herpetic cervicitis: 1 ml of gel is applied with cotton with a swab on the surface of the cervix pre-cleaned of mucus 2 times / day for 7 days, if necessary, the duration of the course can be increased up to 14 days. Rules for using the gel: On the mucous membrane but After cleansing the nasal passages, the gel cavity is applied to the surface of the tonsils 30 minutes after eating. When applying the gel on the tonsils, do not touch the tonsils with a cotton swab, but only gel, while the gel flows down along the surface of the tonsils. When applied gel on the cervix should be removed with a cotton swab or gauze swab mucus and discharge from the vaginal and cervical vaults. When applying the gel on the affected skin and mucous membranes after 30-40 minutes a thin film is formed on otorrhea newly applied formulation.If desired, the film can be peeled off or washed off with water before reapplying the preparation.
Side effects
Allergic reactions: very rarely - skin rash, itching.
Overdose
Data on drug overdose is not provided.
Interaction with other drugs
The drug is well combined with all drugs that are used in the treatment of the above diseases (antibiotics, chemotherapy, GCS).
special instructions
The preparation with impaired integrity of packaging and changed color is not suitable for use.