Bacteriophage coliprotein solution 100 ml
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Active ingredients
Bacteriophage if
Release form
Solution
Composition
One vial of Coliprotein Bacteriophage contains 100 ml of sterile phagolysate of microorganisms Proteus vulgaris, mirabilis and enteropathogenic Escherichia coli strains of different serogroups. The additional substance is 8-hydroxyquinoline sulfate monohydrate.
Pharmacological effect
Antibacterial specific action.
Pharmacokinetics
Peculiarities of pharmacokinetics have not been studied.
Indications
Therapy and prevention of purulent-inflammatory diseases, intestinal infections and dysbacteriosis associated with strains of the genus Proteus and enteropathogenic Escherichia coli as part of a multicomponent treatment: lesions of the digestive tract (intestinal dysbacteriosis, gastroenterocolitis, cholecystitis), diseases of the newborn purulent inflammatory, gastroenterocolitis, cholecystitis), diseases of the newborn purulent inflammatory disorder, gastroenterocolitis, cholecystitis), diseases of the newborn inflammatory, intestinal dysbacteriosis, gastroenterocolitis, cholecystitis, inflammatory diseases of the intestinal tract, gastroenterocolitis, cholecystitis, inflammatory diseases of the digestive tract; gastroenterocolitis, omphalitis, pyoderma, sepsis, conjunctivitis); surgical diseases (hydradenitis, wound suppuration, paraproctitis, osteomyelitis, panaritium, mastitis, carbuncle, fl Egmona, boils, burns, pleurisy, abscess); urogenital infections (pyelonephritis, cystitis, urethritis, colpitis, endometritis, salpingo-oophoritis); diseases of the ear, nose, throat, respiratory tract and lungs (angina, otitis, laryngitis, pharyngitis, pneumonia, pneumonia, respiratory and lung) , pleurisy); generalized septic lesions; other diseases associated with Proteus or E. coli.
Contraindications
Sensitization to the drug.
Use during pregnancy and lactation
Use of the drug is allowed under the supervision of a physician.
Dosage and administration
Instructions for Bacteriophage coliprotein allows the use of the drug inside, in the form of irrigation, applications, enemas, introduction into the nasal cavity, wounds, uterus, vagina, sinuses, as well as for drainage cavities. Recommended dosages for patients older than 8 years are up to 30 ml of the solution when taken orally and up to 50 ml when administered as enemas. Treatment of localized diseases of purulent-inflammatory nature should be carried out by combining local treatment and taking the drug orally for 1-3 weeks. Depending on the nature of the infection, the agent can be applied in the following ways. In the form of lotions, plugging and irrigation in an amount up to 200 ml.With an abscess after emptying its cavity, the drug is administered orally in a smaller amount than the amount of pus removed. In the treatment of osteomyelitis, 10-20 ml of the agent is introduced into the wound after surgical treatment of the wound surface. When inserted into the pleural, articular or other limited cavities, capillary drainage is established, by means of which the medicine is administered 100 ml per day for several days. In pyelonephritis, cystitis, Urethritis is taken orally. In the case of drainage of the pelvis of the kidney or bladder, the drug is administered through a stoma twice a day, 30-40 ml into the cavity of the bladder or 6-7 ml into the renal pelvis. When gynecological lesions of a purulent-inflammatory character are injected into the uterus or vagina, 7-10 ml every day. In case of colpitis, they are treated with 10 ml irrigation or tampons for 2 hours twice a day. In case of throat, ear and nose diseases of purulent-inflammatory nature, the agent is administered 2-10 ml up to three times a day. Bacteriophage is used for washing, instillation, rinsing, or administering turunda for one hour. For intestinal dysbacteriosis and enteric infections, the drug is taken orally three times a day before the meal. The combination of double oral administration with a joint rectal administration of an age dose once a day in the form of an enema after a bowel movement is also permitted. The use of the drug in children under 6 months, including premature infants. up to three times a day. It is also possible to use through the mouth (in the absence of vomiting) by mixing with breast milk. The treatment lasts up to 15 days. In order to prevent enterocolitis, sepsis during intrauterine infection or the risk of nosocomial infection in newborns, the drug is used twice a day in the form of enemas during the week. a napkin twice a day.
Side effects
Not found.
Overdose
Such cases are not described.
Interaction with other drugs
The drug is allowed to combine with anti-inflammatory and antibacterial agents. If antiseptics were used for the treatment before using the bacteriophage, then the wound should be washed with sodium chloride solution.
special instructions
Before use, the bottle with the drug must be shaken and its transparency and the presence of sediment should be evaluated.If turbidity or sediment is detected, the drug should not be used! Due to the presence in the preparation of a favorable climate for the development of microorganisms from the environment that cause clouding of the solution, the vial should be opened according to the following rules: hands should be thoroughly cleaned; the cap should be removed without removing the stopper; the preparation from the opened container should be removed only by piercing the stopper with a sterile syringe; if during the opening together If a stopper was accidentally uncorked with a cap, it should not be placed on the inner surface of the table, and the vial should not be left open (after withdrawing the agent it should be closed with a stopper); the opened vial should be stored in the refrigerator. If these rules are observed and there is no turbidity, It is allowed to use the opened bottle during the whole shelf life period. Children Standard doses of the drug for children up to 6 months are 5 ml when taken orally and 10 ml when used as an enema; for children 6-12 months - 10 ml when administered orally and 20 ml when used as an enema; for children 1-3 years old - 15 ml when taken orally and 20-30 ml when used as an enema; for children 3-8 years old - 20 ml when administered orally and 30-40 ml when used as an enema. In children older than eight years, use adult doses of the drug. For newborns, the standard dose for newborns is 5 ml of the drug when taken orally and 10 ml when used as an enema.