Bacteriophage Klebsiella pneumonia, vial solution 20 ml N4
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Description
Bacteriophage Klebsiella pneumonia, the solution in the vial - immunobiological preparation - bacteriophage. The drug causes a specific lysis of bacteria Klebsiella pneumoniae.
Active ingredients
Bacteriophage klebsiella pneumonia
Release form
Solution
Composition
Sterile purified filtrate of phagolysate Klebsiella pneumonia 10 ml. Excipients: 8-hydroxyquinoline sulfate monohydrate 0.0001 g / ml.
Pharmacological effect
The drug causes a specific lysis of bacteria causative agents of bacterial dysentery.
Indications
Treatment and prevention of diseases caused by bacteria Klebsiella pneumonia in the complex therapy: - diseases of the gastrointestinal tract (gastroenterocolitis, cholecystitis, pancreatitis, intestinal dysbiosis) - inflammatory diseases of infants and young children (gastroenterocolitis, intestinal dysbiosis, omphalitis, pemphigus, pyoderma , septicemia and septicopyemia of different localization), - surgical infections (wounds suppuration, purulent skin lesions, burns, peritonitis, pleurisy, mastitis, osteomyelitis, abscess), - urogenital infections (cystitis, pyelonephritis, urethritis, endometritis, vulvitis, bartholinitis, colpitis, salpingoophoritis), - purulent-inflammatory diseases of the ear, throat, nose, sinuses of the nose, mouth, throat, larynx, bronchi, lungs and pleura (otitis, angina, pharyngitis, laryngitis, stomatitis, periodontitis, sinusitis, frontal sinusitis, bronchitis, pneumonia, pleurisy), - post-traumatic conjunctivitis, keratoconjunctivitis, purulent corneal ulcer and iridocyclitis, - prevention of nosocomial infections caused by Klebsiella. accurate determination of the pathogen sensitivity of the pathogen.
Contraindications
- hypersensitivity to the drug.
Precautionary measures
In case of turbidity, do not use the drug! Due to the content in the preparation of a nutrient medium in which bacteria can develop from the environment, causing clouding of the drug, it is necessary to observe the following rules when opening the bottle: - wash hands thoroughly, - handle the cap with an alcohol-containing solution, - remove the cap, not opening the stoppers, - do not put the stopper with the inner surface on the table or other objects, - do not leave the bottle open, - store the opened bottle only in the refrigerator. When using small doses (2-8 drops) pr It is necessary to select the preparation with a sterile syringe in the amount of 0.5-1 ml. The preparation from the opened vial under the storage conditions,The above rules and the absence of turbidity can be used during the entire shelf life.
Use during pregnancy and lactation
The use of this drug during pregnancy and during breastfeeding is possible in the presence of infections caused by the phagnosensitive Klebsiella strains (as recommended by the doctor).
Dosage and administration
It is permissible to use the drug inside, topically for irrigation and application, rectally, by introducing into the nasal cavity, wounds, uterus, vagina, as well as for drainage cavities. Recommended dosages for patients older than 8 years are up to 30 ml of the solution when taken orally and up to 50 ml when administered as enemas. Treatment of localized diseases of purulent-inflammatory nature is carried out by combining local treatment and taking the drug inside. When treating pharyngitis, sore throats, laryngitis, Klebsiella pneumonia bacteriophage is used in 10-15 ml for rinsing the mouth and throat three times a day for up to 10 days. therapy of bronchitis, pneumonia is prescribed by mouth for 15-20 ml three times a day, and also used in the form of inhalation. The course of therapy is 2-3 weeks. Otitis therapy is carried out using the drug in 3-5 ml for washing and administering to the middle ear up to 3 times a day for up to 2 weeks. When treating inflammation of the sinuses, the medicine is used in 7-10 ml washing the nose, nasopharynx and nasal sinuses, and 3 ml each for the administration in these sinuses once daily for 8-10 days. Also, the solution is injected into the nasal cavity in the form of a turunda moistened with bacteriophage for half an hour. This procedure is carried out three times a day for up to 2 weeks. In the treatment of stomatitis and chronic periodontitis, 15–20 ml of the product is used to rinse the mouth up to four times a day, and also moistened turunda are introduced into the periodontal pockets for 7–10 minutes. The duration of therapy is 8-10 days. In keratoconjunctivitis and conjunctivitis, the remedy is instilled 2-3 drops up to five times a day during the week, with cornea ulcer - 3-4 drops per day for 8-10 days, with iridocyclitis (purulent ) 7-8 drops of solution are instilled every 3 hours and consumed orally in therapeutic dosages for 8-10 days. In an abscess after emptying its cavity, Klebsiell pneumonia is administered orally in a smaller amount than the amount of pus removed.In the treatment of osteomyelitis, 10-20 ml of the solution is applied to the wound after surgical treatment. If necessary, a capillary drainage is established in the pleural, articular or other confined cavities, by means of which the medicine is injected every day for 3-5 days with 100 ml of pyelonephritis and cystitis Urethritis is taken orally. If the cavity of the renal pelvis or bladder is drained, the drug is administered through a drainage tube twice a day, 30-40 ml into the cavity of the bladder or 6-7 ml into the renal pelvis. In gynecological diseases of purulent-inflammatory nature, the agent is introduced into the vagina or uterus 7-10 ml every day. With colpitis, treatment is carried out by irrigation with 10 ml or plugging twice a day for 2 hours. With intestinal dysbiosis and pancreatitis, cholecystitis, gastroenterocolitis, the remedy is taken orally three times a day one hour before meals for 1-3 weeks. A combination of double oral administration with a single rectal administration of an age dose per day in the form of an enema is also permitted. In the therapy of purulent wounds, the Klebsiella pneumonia bacteriophage is used in the form of applications, dressings, irrigation, and 10-50 ml of drainage at least 1 time per day for 10-15 days. To prevent hospital surgical infections, 5 to 50 ml of the product is treated with freshly infected and postoperative wounds once a day every day. The use of the drug in children under 6 months of age, including donoshennyhPri pneumonia gastroenterocolitis, neonatal sepsis Bacteriophage Klebsiella pneumonia apply 4-5 ml orally 2-3 times a day for half an hour before feeding. If unrestrained vomiting is present, then 7-10 ml of the medicine is used once daily for high enema. The combined use of rectal and oral route of administration of the drug is allowed. The course of therapy lasts for 1-2 weeks. In order to prevent the occurrence of nosocomial infections in newborns, the medication is used for epidemic indications of 4-5 ml orally three times a day for half an hour before feeding the entire hospital stay. When treating pyoderma, omphalitis, septic wounds, the remedy is in the form of applications soaked in a clean cloth, which is applied to the wound surface twice a day.
Side effects
Not installed.
Overdose
Not installed.
Interaction with other drugs
The use of the drug is possible in combination with other drugs, including antibiotics.
special instructions
Contraindications to the use of: hypersensitivity to the drug.