Pyobacteriophage complex solution for local use and ingestion 20 ml
Condition: New product
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Active ingredients
Pyobacteriophage
Release form
Solution
Composition
1 vial contains: The mixture was purified filtrates fagolizatov bacteria Staphylococcus, Streptococcus, Proteus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli ml.Konservant 20: 8-hydroxyquinoline sulfate - 0.0001 g / ml (calculated content) or 8-hydroxyquinoline sulfate monohydrate - 0.0001 g / ml (in terms of hydroxyquinoline sulfate, the calculated content).
Pharmacological effect
The drug has the ability to specifically lyse the bacteria Staphylococcus, Streptococcus, Proteus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli.
Indications
Treatment and prevention of various forms of purulent-inflammatory and enteral diseases caused by bacteria Staphylococcus, Streptococcus, Proteus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli: - Gastrointestinal diseases (gastroenterocolitis, cholecystitis, pancreatitis, I have a unaccepantal control system, cholecystitis, pancreatitis; age (gastroenterocolitis, intestinal dysbiosis, omphalitis, pemphigus, pyoderma, septicemia, and septicopyemia of various localization); - Surgical infections (wound suppuration, purulent skin lesions, burns, peritonitis, pleurisy, t, osteomyelitis); - Urogenital infections (cystitis, pyelonephritis, endometritis, vulvitis, bartholinitis, colpitis, salpingoophoritis); - Pyo-inflammatory diseases of the ear, throat, nose, sinuses of the nose, oral cavity, pharynx, larynx, lungs and pleura , angiopathy coli.Important An effective phage therapy is the preliminary determination of the pathogen sensitivity of the pathogen.
Contraindications
None.
Use during pregnancy and lactation
Unlike antibiotic therapy, which is not highly recommended during pregnancy, the treatment of purulent infections with the help of bacteriophage during this period (as well as breastfeeding) has no contraindications due to the narrow specificity of bacteriophages only to specific types of bacterial cells, and the absence of their influence on other cells organism.
Dosage and administration
Before using the bottle with a bacteriophage must be shaken and viewed.The drug must be clear and free of sediment. Attention! In case of turbidity, do not use the drug! Due to the content in the preparation of the nutrient medium in which bacteria can develop from the environment, causing clouding of the drug, it is necessary when opening the bottle to observe the following rules: - wash hands thoroughly - process the cap with an alcohol-containing solution; remove the cap without opening the stopper; - do not put the stopper with the inner surface on the table or other objects; - do not leave the bottle open; - keep the opened bottle only in the refrigerator. When using small doses (2-8 drops), the preparation should be taken with a sterile syringe in volume 0.5-1 ml. A preparation from an opened bottle, under the conditions of storage, the above rules and the absence of turbidity can be used during the whole shelf life. The preparation is used for oral (mouth) administration, in the form of enemas, applications, irrigations, conducting in the cavity of wounds, vagina, uterus, nose, sinuses, and also in the drained cavity: abscesses, abdominal, pleural, bladder, renal pelvis. Inside the drug is taken on an empty stomach 0.5-1 hour before meals. Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and taking the drug inside. In case of treatment of the cavity of a purulent focus with chemical antiseptics, before using the bacteriophage, it should be washed with a sterile 0.9% sodium chloride solution. vines, pharyngitis, laryngitis are used for rinsing the mouth and pharynx 3 times a day for 10-20 ml, the course of treatment is 7-10 days. When treating bronchitis, pneumonia, the drug is taken orally 3 times a day for 10-20 ml, and used in the form of aerosols and inhalations (without heating and using ultrasound), the course of treatment is 15-20 days. When treating otitis, the drug is used for washing and inserting into the middle ear cavity 2-5 ml 1-3 times a day. The course of treatment is 7-15 days. In the treatment of inflammation of the sinuses of the nose, the drug is used for washing the nasal cavity, nasopharynx and sinuses in a dose of 5-10 ml and injecting 2-3 ml into the sinuses. The procedure is repeated daily once for 7-10 days. In addition, the drug is injected into the nasal cavity in the form of turunda, moistened with bacteriophage, in turn in each nasal passage and left for 0.5-1 hour.The procedure is repeated 3 times a day, the course of treatment is 7-15 days. In the treatment of stomatitis and chronic periodontitis, the drug is used in the form of mouth rinses 3-4 times a day at a dose of 10-20 ml, as well as the introduction of turunds soaked in bacteriophage into the paradontal pockets , for 5-10 minutes, the course of treatment is 7-10 days. When conjunctivitis and keratoconjunctivitis, the drug is used 2-3 drops 4-5 times a day, the course of treatment is 5-7 days; with purulent corneal ulcer - 4-5 drops per day for 7-10 days, with purulent iridocyclitis - 6-8 drops every 3 hours in combination with ingestion in therapeutic dosages for 7-10 days. When abscess after opening and removal of purulent contents, the drug is administered in an amount less than the volume of the removed pus once a day, a course of treatment is 7-10 days. In peritonitis and pleurisy, the drug is injected into the drained cavities - abdominal and pleural through the drainage tubes once daily 20-70 ml, the course of treatment 10 -15 days. When osteomyelitis pre Arat is injected into the wound cavity through turunds, drainage in the amount of 10-30 ml daily once, a course of treatment is 15-20 days. When treating mastitis, wounds and burns suppuration, the drug is used in the form of irrigation, applications, dressings, administration in the drainage in a dose of 5 -50 ml depending on the lesion at least 1 time per day, the course of treatment is 10-15 days. In the treatment of purulent-inflammatory gynecological diseases (wounds suppuration, endometritis, vulvitis, bartholinitis, colpitis, salpingoophoritis), the preparation is used for irrigation, applications, injected into the cavity of wounds, vagina, uterus 5-20 ml once a day for 7-10 days. In case of cystitis, pyelonephritis, urethritis, the drug is taken orally in a therapeutic dose 3 times a day 1 hour before meals for 10-20 days. In that case, if the cavity of the bladder or the renal pelvis is drained, the drug is administered through a cystostom or nephrostomy 1-3 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis, the course of treatment is 7-15 days. Gastroenterocolitis, pancreatitis, cholecystitis, and intestinal dysbiosis bacteriophage are taken orally in age dosages 3 times a day 1 hour before meals for 7-15 days (for clinical reasons). When indomitable vomiting drug is used in the form of high enemas 2-3 times a day, 20-40 ml. For intestinal dysbiosis, the drug can be used with normoflora preparations. For the prevention of nosocomial surgical infectionsThe drug is used for treatment of postoperative and freshly infected wounds in a dose of 5-50 ml depending on the lesion every day for 5-7 days. Use of the drug in children under 1 year old (including premature babies) For gastroenterocolitis, pneumonia and sepsis of newborns, the drug is used through mouth 2-3 times a day, 3-5 ml for 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a vapor tube or catheter) once daily in a dose of 5-10 ml. Perhaps a combination of rectal (in the form of high enemas) and oral administration of the drug. The course of treatment is 7-15 days (according to clinical indications). In the case of a relapsing course of the disease, repeated courses of treatment are possible. When treating omphalitis, pyoderma, infected wounds, the bacteriophage is used in the form of applications of 5-10 ml 2-3 times a day (a gauze cloth is moistened with a bacteriophage and applied to the umbilical wound or the affected area of skin) for 7-15 days. With the aim of preventing the onset of nosocomial infections in newborns, the bacteriophage is used according to epidemic indications by mouth for 3-5 ml 3 times a day 30 minutes before feeding during the entire period of stay in the hospital.
Side effects
Not installed.
Overdose
Cases of drug overdose Pyobakteriofag not registered.
Interaction with other drugs
The use of the drug does not preclude the use of other antibacterial and anti-inflammatory drugs.
special instructions
The use of bacteriophage does not preclude the use of other drugs, including antibacterial and anti-inflammatory drugs. An important condition for effective phage therapy is a preliminary determination of the pathogen sensitivity of the pathogen.