More info
Description
Tablets biconvex oval-shaped, film-coated white color with risky on one side.
Active ingredients
Multivitamins + Minerals
Release form
Pills
Composition
1 tablet contains active ingredients: calcium (calcium citrate tetrahydrate and calcium carbonate) 250 mg, vitamin B (colecalciferol) 50 IU, zinc (zinc oxide) 2 mg, copper (copper oxide) 0.5 mg, manganese (manganese sulfate) 0, 5 mg boron (sodium borate decahydrate) 50 mcg. Excipients: soy polysaccharide 10 mg, sodium lauryl sulfate 5 mg, colloidal silicon dioxide 3.9 mg, croscarmellose sodium 28 mg, microcrystalline cellulose 199.45 mg, stearic acid 35 mg, magnesium stearate 10 mg. Shell: hypromellose 11.71 mg , triacetin 2.53 mg, mineral oil 1.27 mg, sodium lauryl sulfate 0.004 mg, titanium dioxide 7.03 mg, magnesium silicate 5 mg.
Pharmacological effect
Combined preparation containing calcium, vitamin D3, osteotropic minerals that regulate calcium metabolism. The pharmacological effect of the drug is determined by the properties of its constituent ingredients. Calcium is involved in the formation of bone tissue, reduces resorption (resorption) and increases bone density, prevents diseases of the musculoskeletal apparatus, helps to strengthen the bone system and joints. Calcium citrate provides calcium absorption, regardless of the functional state of the gastrointestinal tract, Enim for the treatment of patients with reduced gastrointestinal secretory function, as well as during treatment with drugs to reduce secretion; reduces the level of markers of bone resorption, which indicates a slowdown in the processes of destruction of bone tissue; regulates the level of parathyroid hormone, which leads to improved regulation of calcium homeostasis; does not increase the content of oxalates and calcium in the urine, therefore does not cause the risk of kidney stones; does not block the absorption of iron, which reduces the risk of iron deficiency anemiaColecalciferol (vitamin D3) regulates the exchange of calcium and phosphorus in the body, participates in the formation of bone skeleton, helps preserve the structure of bones, enhances calcium absorption in the intestine and reabsorption of phosphorus in the renal tubules. Zinc promotes the synthesis of sex hormoneswhich prevents the destruction of bone tissue. Manganese is involved in the formation of proteoglycans, which improves the quality of bone tissue and forms the protein matrix of bone tissue. Copper participates in the synthesis of collagen and elastin, which is part of the bone and connective tissue, which affects the formation of bone mass. Bor reduces excessive activity of parathyroid hormone, improves calcium absorption, reduces the risk of cholecalciferol deficiency, helps prevent osteoporosis.
Indications
Prevention and complex treatment of osteoporosis of various origins. To compensate for calcium deficiency and trace elements in children, adolescents and women during pregnancy and breastfeeding.
Contraindications
Increased individual sensitivity to any of the components of the drug, hypercalcemia and hypercalciuria, nephrolithiasis, vitamin D3 hypervitaminosis, severe renal failure, active tuberculosis, decalcification tumors (myeloma, bone metastases, sarcoidosis), children up to 5 years.
Precautionary measures
Benign granulomatosis, taking cardiac glycosides and thiazide diuretics, pregnancy, lactation.
Use during pregnancy and lactation
During pregnancy and breastfeeding, the drug should be coordinated with the doctor. The daily dose should not exceed 1500 mg of calcium and 600 IU of vitamin D3, hypercalcemia that develops during an overdose during pregnancy can cause defects of mental and physical development in the fetus. Nursing women should take into account that colecalciferol and its metabolites pass into breast milk, therefore it is necessary to take into account the intake of calcium and vitamin D3.
Dosage and administration
Inside. For children from 5 to 12 years old, take 1 tablet 1 time per day with meals. Adults and children over 12 years old - 1 tablet 2 times per day with food. During pregnancy and breastfeeding: from the 20th week pregnancy and the entire period of breastfeeding - 1 tablet 2 times a day. The minimum course of taking the drug for treating osteoporosis as part of complex therapy for adults is 3 months, a longer course - after consulting a doctor. The minimum course of taking the drug for preventing osteoporosis for adults composition yaet 1 montha longer course - after consulting a doctor. The minimum course of taking the drug for children and adults with calcium and trace element deficiencies is 2-3 months, a longer course - after consulting a doctor. A second course of taking the drug is possible 1 month after the end of treatment.
Side effects
Nausea, vomiting, flatulence, diarrhea, constipation, hypercalcemia and hypercalciuria, allergic reactions (itching, rash, urticaria).
Interaction with other drugs
With simultaneous use of the drug Calcemin with vitamin A decreases the toxicity of vitamin D3. Phenytoin, barbiturates, glucocorticoids reduce the effectiveness of vitamin D3. Laxatives reduce the absorption of vitamin D3. Glucocorticoids, hormonal contraceptives for systemic use, levothyroxine worsen the absorption of calcium ions. With the simultaneous use of tetracyclines, the interval between doses must be at least 3 hours, bisphosphonates and sodium fluoride (their absorption is disturbed) - at least 2 hours. With the joint use of the drug Kalcemin with cardiac glycosides, their toxicity increases (ECG and clinical condition monitoring is necessary), with thiazide diuretics - the risk of hypercalcemia increases, with furosemide and other loop diuretics - calcium excretion by the kidneys increases. Do not use Calcemin in conjunction with calcium channel blockers. It is not recommended to take the drug with antacids, which contain aluminum, due to a decrease in their effectiveness.
special instructions
The dose should not exceed that specified in the instructions, since increased calcium intake may inhibit the absorption in the intestine of iron, zinc and other essential minerals. Effect on ability to drive and drive mechanisms: No effect.
Storage conditions
At a temperature not higher than 25 ° C. Keep out of the reach of children.