Cardique retard pills with prolonged action 40mg N50
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Description
Cardict pills retard of prolonged action - peripheral vasodilator with a predominant effect on the venous vessels. Cardict has antianginal and hypotensive effects. The mechanism of action is associated with dilatation of the blood vessels (mainly postcapillary) and large arteries. Dilatation of the vessels of the postcapillary bed leads to venous deposition of blood and a decrease in venous return of blood to the heart. As a result of lowering of the left ventricle filling (preload reduction), myocardial oxygen demand decreases, which increases capillary blood flow, opens the lumen of previously inactive intramural coronary vessels, and improves oxygen supply to the ischemic subendocardial region. Dilatation of precapillary vessels leads to a decrease in systolic pressure in the aorta and OPSS (afterload reduction). As a result, the cardiac output of the left ventricle and the myocardial oxygen demand are reduced. Direct dilatation of the coronary vessels and a small decrease in the resistance of the coronary vessels improve myocardial perfusion and supply it with oxygen without developing the stealing syndrome.
Active ingredients
Isosorbide dinitrate
Release form
Pills
Composition
Active ingredient: isosorbid dinitrate 40 mg. Excipients: lactose monohydrate, talc, magnesium stearate, polyvinyl acetate, potato starch.
Indications
Prevention of strokes, rehabilitation after myocardial infarction, pulmonary hypertension, chronic heart failure (as part of combination therapy).
Precautionary measures
Before use, consult with your doctor.
Use during pregnancy and lactation
Use of the drug Cardict during pregnancy is possible only when the intended benefit to the mother outweighs the potential risk to the fetus. If necessary, the appointment of the drug during lactation should decide on the termination of breastfeeding.
Dosage and administration
The dose is selected individually, since it depends on the stage of the disease and the individual need for nitrates. 40 mg pills - 1 tab. 2 times / day.The drug should be taken after meals, without chewing and squeezing a small amount of liquid. With the appointment of more than 1 tab. / Day interval between doses should be at least 8 hours (to ensure the full effect of the drug).
Side effects
Since the cardiovascular system: at the beginning of treatment - severe headache (due to dilatation of the cerebral venous bed), possibly - tachycardia, orthostatic hypotension. CNS: drowsiness. From the digestive tract: in some cases - nausea, vomiting. Dermatological reactions: in some cases - erythematous rash.
Overdose
Symptoms: headache, palpitations, dizziness, arterial hypotension, nausea, vomiting. Treatment: symptomatic.
Interaction with other drugs
With simultaneous use of Cardict retard with antihypertensive drugs, cyclic antidepressants, MAO inhibitors, it is possible to enhance its hypotensive action. With simultaneous use Cardiket retard potentiates the action of dihydroergotamine and ethanol.
special instructions
Contraindications: acute myocardial infarction, acute circulatory failure (shock, vascular collapse), severe hypotension (systolic blood pressure less than 90 mm Hg). Cardique retard should not be prescribed to relieve angina pectoris. Severe headache that occurs at the beginning of therapy, in most cases, decreases significantly or completely disappears while continuing to take the drug. Alcohol should be avoided during treatment with Cardichet. Impact on the ability to drive motor vehicles and control mechanisms: the question of the possibility of practicing potentially hazardous activities should be addressed only after evaluating the patient's individual response to the drug.