Cavinton concentrate for infusions 5 mg 1 ml 10 ml ampoules N5,
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Active ingredients
Vinpocetine
Composition
1 ml of 1 amp. Vinpocetine 5 mg 50 mg. Excipients: ascorbic acid - 0.
Pharmacological effect
A drug that improves cerebral circulation and brain metabolism. It improves brain metabolism by increasing the consumption of glucose and oxygen by the brain tissue. Increases the resistance of neurons to hypoxia. enhancing glucose transport to the brain through the BBB. translates the process of the breakdown of glucose to an energetically more economical, aerobic way. selectively blocks Ca2 + -dependent phosphodiesterase. increases levels of adenosine monophosphate (AMP) and cyclic guanosine monophosphate (cGMP) of the brain. Increases ATP concentration in brain tissue. enhances the exchange of norepinephrine and brain serotonin. stimulates the ascending branch of the noradrenergic system, has an antioxidant effect. Reduces platelet aggregation and increased blood viscosity. increases the deforming ability of erythrocytes and blocks the utilization of adenosine by erythrocytes. contributes to increased oxygen return by red blood cells. Enhances the neuroprotective effect of adenosine. Increases cerebral blood flow. reduces the resistance of cerebral vessels without significant changes in systemic blood circulation (BP, minute volume, heart rate, OPS). It does not have the effect of “stealing”, increases blood supply, especially in ischemic brain regions with low perfusion.
Indications
- reducing the severity of neurological and mental symptoms in various forms of circulatory insufficiency of the brain (ischemic stroke, recovery stages of hemorrhagic stroke, the effects of a stroke, transient ischemic attack, vascular dementia, vertebrobasilar insufficiency, cerebral vascular atherosclerosis, post-traumatic, I, I, and I, I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I, and I and I will have to do it. eyes (for example, thrombosis / occlusion / center flax artery or retinal vein) - for the treatment of perceptual hearing loss, Meniere's disease, idiopathic tinnitus.
Contraindications
- acute phase of hemorrhagic stroke - severe form of coronary artery disease - severe arrhythmias - pregnancy - lactation period - age up to 18 years (due to insufficient data) - hypersensitivity to the drug components.
Use during pregnancy and lactation
The drug is contraindicated in pregnancy and lactation.
Side effects
Side effects against the use of the drug were rarely detected. On the part of the cardiovascular system: ECG change (ST depression, prolongation of the QT interval), tachycardia, extrasystole (causal relationship with taking the drug has not been proven, because in the natural population these symptoms are observed with the same frequency). change in blood pressure (often reduced), redness of the skin, phlebitis. On the part of the central nervous system: sleep disorders (insomnia, increased sleepiness), dizziness, headache, general weakness (these symptoms may be manifestations of the underlying disease). On the part of the digestive system: dry mouth, nausea, heartburn. Other: skin allergic reactions, increased sweating.
special instructions
Side effects against the use of the drug were rarely detected. On the part of the cardiovascular system: ECG change (ST depression, prolongation of the QT interval), tachycardia, extrasystole (causal relationship with taking the drug has not been proven, because in the natural population these symptoms are observed with the same frequency). change in blood pressure (often reduced), redness of the skin, phlebitis. On the part of the central nervous system: sleep disorders (insomnia, increased sleepiness), dizziness, headache, general weakness (these symptoms may be manifestations of the underlying disease). On the part of the digestive system: dry mouth, nausea, heartburn. Other: skin allergic reactions, increased sweating.