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Active ingredients
Caffeine + Paracetamol + Phenylephrine + Terpingidrate + Ascorbic Acid
Release form
Pills
Composition
Paracetamol 500 mg, caffeine 25 mg, phenylephrine hydrochloride 5 mg, terpinehydrate 20 mg, ascorbic acid 30 mg.
Pharmacological effect
Combined drug for symptomatic treatment of acute respiratory diseases. Paracetamol has analgesic and antipyretic effects, phenylephrine reduces swelling of the mucous membranes and sinuses, resulting in easier breathing, caffeine has a general tonic effect, ascorbic acid (vitamin C) fills the increased need for vitamin A, vitamin A, has a general tonic effect, ascorbic acid (vitamin C) fills the increased need for vitamin E. flu.
Pharmacokinetics
Data on the pharmacokinetics of the drug Coldrex not provided.
Indications
Coldrex pills provide relief from symptoms of colds and flu, such as fever, headache, chills, pain in the joints and muscles, a feeling of nasal congestion, pain in the sinuses and in the throat.
Contraindications
The drug should not be taken simultaneously with other paracetamol-containing drugs, with increased sensitivity to the ingredients that make up the drug, with a genetic absence of glucose-6-phosphate dehydrogenase, with diseases of the blood system, with severe violations of the liver or kidney function, thyrotoxicosis, diabetes, arterial hypertension.
Precautionary measures
Do not exceed recommended doses.
Use during pregnancy and lactation
With caution and only after consulting a doctor can you take the drug during pregnancy and lactation.
Dosage and administration
Adults and children over 12 years: 2 pills up to 4 times a day. Children (6-12 years): 1 tablet up to 4 times a day. Do not give the drug to children under 6 years old without consulting a doctor. The drug is not recommended for more than five days without consulting a doctor. If symptoms persist, consult a doctor. Do not exceed the specified dose. In case of overdose, seek medical attention immediately, even if you feel well.
Side effects
In recommended doses, the drug is usually well tolerated. Paracetamol rarely has a side effect.Sometimes allergic reactions are possible, for example, skin rash, urticaria, angioedema. Rarely - disorders of the blood picture. With prolonged use in excess of the recommended dose can be observed hepatotoxic and nephrotoxic effects. Acetylcysteine is a specific antidote for paracetamol poisoning. Phenylephrine may cause nausea, headache, a slight increase in blood pressure and, in rare cases, palpitations that pass after drug withdrawal. Excessive consumption of tea or coffee while taking Coldrex can cause irritability and nervous tension
Overdose
In case of an overdose, you should immediately seek medical help, even if you feel well. Symptoms: nausea, vomiting, stomach pain, sweating, pale skin, cardiac arrhythmias. After 1-2 days, signs of liver damage can be detected. In severe cases, liver failure and coma develops. Treatment: make a gastric lavage during the first 4 hours after taking the drug, then carry out symptomatic therapy. Acetylcysteine is a specific antidote for paracetamol poisoning.
Interaction with other drugs
The drug should not be taken simultaneously with tricyclic antidepressants, beta-blockers, MAO inhibitors, and within 14 days after they are canceled. Domperidone increases the rate of absorption of paracetamol, and Kolestiramin - reduces.
special instructions
Excessive consumption of tea or coffee while taking Coldrex can cause irritability and nervous tension. In order to avoid toxic damage to the liver, patients taking Coldrex should refrain from drinking alcohol. It is not recommended to prescribe the drug for chronic alcoholism. Use in pediatricsWithout the advice of a doctor, you cannot use the drug in children under 6 years of age.