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Description
Familar pills are an antiviral agent. They are used to treat infections caused by the Varicella zoster virus (shingles, including shingles with ocular complications), infections caused by the Herpes simplex virus (primary infection, exacerbation of chronic infections, suppression of recurrent infections).
Active ingredients
Famciclovir
Release form
Pills
Composition
Active ingredient: famciclovir 500 mg. Auxiliary substances: microcrystalline cellulose - 305 mg, croscarmellose sodium - 50 mg, lactose monohydrate - 200 mg, crospovidone XL-10 - 45 mg, magnesium stearate - 12 mg, colloidal silicon dioxide - 5 mg, talc - 3 mg. The composition of the shell: opadry white - 14 mg (polyvinyl alcohol (hydrolyzed) - 38.6%, titanium dioxide - 30%, talc - 17.5%, macrogol 4000 - 10.9%, lecithin - 3%), hypromellose - 1.2 mg, macrogol 4000 - 0.04 mg, polysorbate 80 - 0.76 mg, titanium dioxide - 4 mg.
Indications
Infections caused by the Varicella zoster virus (shingles, including shingles with ocular complications), infections caused by the Herpes simplex virus (primary infection, exacerbation of chronic infections, suppression of recurrent infections).
Precautionary measures
Use with caution in patients with impaired renal function. In the presence of clinical manifestations of genital herpes, even if antiviral treatment is initiated, patients should avoid sexual intercourse.
Use during pregnancy and lactation
Contraindicated in pregnancy and lactation.
Dosage and administration
Treatment should begin immediately after diagnosis. When ingested a single dose - 250-500 mg. The frequency and duration of use depend on the evidence, immune status, renal function, treatment effectiveness.
Side effects
Possible: mild and moderate headaches, nausea. Rarely: vomiting, dizziness, skin rash, mainly in elderly patients - confusion, hallucinations. In patients with reduced immunity: possible abdominal pain, fever, rarely - granulocytopenia and thrombocytopenia.
Interaction with other drugs
Probenecid and other drugs that affect kidney function may alter penciclovir plasma levels.
special instructions
Contraindications: hypersensitivity to famciclovir and penciclovir.Use during pregnancy and lactation Because the safety of famciclovir during pregnancy and lactation has not been studied, the use is not recommended unless the expected benefit of therapy for the mother outweighs the potential risk to the fetus or infant. It is not known whether penciclovir is excreted in human breast milk. Famciclovir does not have a pronounced effect on the spermogram, morphology or motility of human sperm. In experimental studies, no embryotoxic and teratogenic effects of famciclovir and penciclovir were detected. Studies on rats fed famciclovir orally have shown that penciclovir is excreted in breast milk. A decrease in fertility was noted in an experimental model in male rats receiving famciclovir at a dose of 500 mg / kg body weight, and in female rats there was no marked decrease in fertility. Application for violations of renal function Use with caution in patients with impaired renal function.