Fenistil gel for external use 30 g
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Active ingredients
Dimetinden
Release form
Gel
Composition
Active ingredient: Dimetindene (Dimetindene) Active ingredient concentration (mg): 1
Pharmacological effect
Histamine h1 receptor blocker. has anti-allergic and antipruritic effect. reduces the increased capillary permeability associated with allergic reactions. when applied to the skin, reduces itching and irritation caused by skin-allergic reactions. the drug also has a pronounced local anesthetic effect. It blocks the action of kinins, has a weak anticholinergic effect. 1-4 hours
Pharmacokinetics
When applied topically, it penetrates the skin well. Systemic bioavailability of the active substance is 10%.
Indications
Pruritus of various origins (other than those associated with cholestasis), for example: pruritic dermatosis, eczema, urticaria, insect bites. Sunburn, household and industrial burns (mild).
Contraindications
Hypersensitivity to dimetindenu and other components of the drug, angle-closure glaucoma, prostatic hyperplasia, children up to 1 month, especially premature.
Precautionary measures
The drug should be stored out of the reach of children, gel at a temperature not higher than 25 ° C.
Use during pregnancy and lactation
Use of the drug Fenistil in the first trimester of pregnancy is possible only after consulting a doctor. In the second and third trimesters of pregnancy and during lactation, the gel should not be used on large areas of the skin, especially if there are signs of inflammation and bleeding. .
Dosage and administration
Outwardly. The gel is applied to the affected skin 2-4 times a day. In cases of severe itching or common skin lesions, the simultaneous use of oral forms is recommended.
Side effects
Dryness, burning skin. In rare cases - skin rash and itching.
Overdose
Symptoms: if a large amount of the drug is accidentally swallowed, symptoms characteristic of histamine H1 receptor blockers may occur - CNS depression and drowsiness (mainly in adults), CNS stimulation and m-anticholinergic effects (especially in children),excitement, ataxia, tachycardia, hallucinations, tonic or clonic convulsions, mydriasis, dry mouth, flushing to the face, urinary retention, fever. This may be followed by a decrease in AD. Treatment: the specific antidote is unknown. It should appoint an activated carbon, saline laxative; carry out activities to maintain the function of the cardiovascular and respiratory systems. For the treatment of arterial hypotension, vasoconstrictor agents may be used. In case of accidental overdose, the patient should consult a doctor.
Interaction with other drugs
Drug interaction of the drug Fenistil is not described.
special instructions
In case of severe itching or damage to large areas of the skin, the drug can be used only after consulting a doctor. When using the drug Fenistil on large areas of the skin, avoid exposure to the sun. ineffective with itching associated with cholestasis. The preparation contains propylene glycol and benzalkonium chloride. The emulsion also contains butylhydroxytoluene. These excipients can cause local allergic reactions (contact dermatitis). Butylhydroxytoluene can also cause irritation of the eyes and mucous membranes. Use in pediatrics In children aged 1 month to 2 years, the drug should be used only after consulting a doctor. In infants and young children, you should not use the drug in large areas of the skin, especially if you have inflammation. or bleeding. Influence on ability to drive motor transport and control mechanismsNot affected.