Glycine-biotics lingual pills 100 mg N50
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Active ingredients
Glycine
Release form
Pills
Composition
1 tablet contains: Active substance: glycine microencapsulated 100 mg. Auxiliary substances: magnesium stearate 1 mg, methyl cellulose soluble in water 1 mg.
Pharmacological effect
Replaceable amino acid, central neurotransmitter inhibitory type of action. It improves the metabolic processes in the brain tissues, has an antidepressant and sedative effect. It has GABA-ergic, alpha-adrenergic blocking, antioxidant and antitoxic action, regulates the activity of glutamate (NMDA) receptors, thereby reducing psycho-emotional stress, aggressiveness and conflict; improves social adaptation and mood, facilitates falling asleep and normalizes sleep, improves mental performance, reduces the severity of vegetative-vascular disorders (including during menopause) and cerebral disorders in ischemic stroke and traumatic brain injury. Reduces the toxic effect of ethanol on the central nervous system.
Pharmacokinetics
It easily penetrates into most biological fluids and body tissues, including the brain, does not accumulate. It is rapidly destroyed in the liver by glycine oxidase to water and carbon dioxide.
Contraindications
Individual hypersensitivity to the drug.
Precautionary measures
With care: arterial hypotension
Use during pregnancy and lactation
The drug is contraindicated during pregnancy and during breastfeeding, due to the lack of sufficient data.
Dosage and administration
Glycine is applied sublingually or transbucally at 0.1 g (in pills or in powder form after grinding pills). Practically healthy children, adolescents and adults with psycho-emotional stress, loss of memory, attention, mental performance, mental retardation, with deviant behaviors glycine is prescribed 1 tablet 2-3 times a day for 14-30 days. With functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbance, children up to three years old are prescribed 0.5 pills (0.05 g) to be taken 2-3 times a day for 7-14 days, further to 0.05 g once a day for 7-10 days.Daily dose - 0.1-0.15 g, course - 2.0-2.6 g. Children older than 3 years and adults are prescribed 1 tablet 2-3 times a day, the course of treatment is 7-14 days. The course of treatment can be increased up to 30 days, if necessary, repeat the course after 30 days .. For sleep disorders, glycine is prescribed 20 minutes before sleep or immediately before going to bedtime with a 0.5-1 tablet (depending on age). In ischemic cerebral stroke: during the first 3-6 hours after stroke development, 1 g is administered transbuccal or sublingually with one teaspoon of water, then for 1-5 days, 1 g per day, then for the next 30 days, 1-2 pills 3 times a day. In narcology, glycine is used as a means of improving mental performance and reducing psycho-emotional stress during remission with symptoms of encephalopathy, organic lesions of the central and peripheral nervous system, 1 tablet 2-3 times a day for 14-30 days. If necessary, courses are repeated 4-6 times a year.
Side effects
Allergic reactions are possible.
Overdose
Data overdose available.
Interaction with other drugs
Weakens the severity of side effects of antipsychotic drugs (neuroleptics), anxiolytics, antidepressants, sleeping pills and anticonvulsant drugs.
special instructions
In patients with a tendency to hypotension Glycine-Bio is taken in smaller doses and under the control of blood pressure, with its decrease below the usual level of admission stops. Influence on ability to drive motor transport and control mechanisms. When taking the drug Glycine-Bio, care should be taken when driving and engaging in other potentially hazardous activities that require high concentration of attention and speed of psychomotor reactions, taking into account the profile of side effects.