Nasic spray nasal for vzr.0,1mg 5mg dose vial 10ml
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Description
Nasic Nasal Spray is a combined nasal preparation for topical use containing Xylometazoline and Dexpanthenol. Xylometazoline belongs to the group of local vasoconstrictor agents (decongestants) with alpha adrenomimetic activity, causes a narrowing of the blood vessels of the nasal mucosa, restores the nasal passability, and facilitates nasal breathing. The effect of the drug usually occurs within a few minutes after its use and lasts up to 10 hours. Dexpanthenol - a vitamin B group - a derivative of pantothenic acid. Dexpanthenol is converted into pantothenic acid in the body, which is an integral part of coenzyme A and is involved in acetylation, carbohydrate and fat metabolism, in the synthesis of acetylcholine, corticosteroids, porphyrins, stimulates the regeneration of the skin, mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases pulsation, and increases pulsation. . It has a regenerating, metabolic and weak anti-inflammatory effect.
Active ingredients
Dexpanthenol + Xylometazoline
Release form
Spray
Composition
Xylometazoline hydrochloride, dexpanthenol, benzalkonium chloride, potassium dihydrophosphate, sodium hydrogen phosphate dodecahydrate, purified water.
Indications
Applied with acute respiratory diseases with symptoms of rhinitis, acute allergic rhinitis, vasomotor rhinitis, sinusitis, with otitis media (as part of combination therapy to reduce swelling of the nasopharyngeal mucosa), to facilitate rhinoscopy, restore impaired nasal breathing after surgical interventions in the nasal cavity.
Precautionary measures
Take with caution to patients taking monoamine oxidase inhibitors (MAO inhibitors) or other drugs that increase blood pressure, patients with pheochromocytoma, patients with metabolic disorders (for example, hyperthyroidism, diabetes).
Use during pregnancy and lactation
Considering that there is no data on the reproductive toxicity of the drug, its use is not recommended during pregnancy and lactation.
Dosage and administration
Intranasalpo. For adults and children over 6 years. When using a bottle with pump dispenser packaged separately.Remove the pump dispenser from the packaging. Uncap the bottle with the preparation, screw the dispensing device on the neck of the bottle, remove the protective cap. The bottle is ready to use. Before the first application of the spray, repeatedly press the pump dispenser until a uniform spray appears. When using a bottle with a built-in pump dispenser. Remove the protective cap from the integrated pump dispenser. The bottle is ready to use. Before the first application of the spray, press the built-in pump dispenser several times until a uniform spray appears. When applying the spray bottle must be kept upright. Breathe in easily with the nose during the injection. One injection in each nasal passage 3-4 times a day. Duration of therapy is 3-5 days.
Side effects
Respiratory, thoracic and mediastinal disorders. Very rarely: temporary, mild irritation (burning or dryness of the nasal mucosa), especially in patients with hypersensitivity. Very rarely or in single messages: increased swelling of the mucous membrane of the nasal cavity. With frequent and / or long-term use or when using large doses of Xylometazoline hydrochloride, burning and paresthesia of the nasal mucosa may occur, the development of reactive edema with rhinitis medicamentosa. This effect may occur as early as 5 days from the start of treatment and with long-term use lead to the development of permanent damage to the mucous membrane with the formation of scabs (rhinitis sicca). Violation of the nervous system. Rarely or very rarely: headache, vomiting, insomnia or fatigue, blurred vision, depression (with prolonged use in high doses). Cardiovascular disorders: palpitations, tachycardia, increased blood pressure. Very rarely: allergic reactions may occur.
Interaction with other drugs
With the simultaneous use of MAO inhibitors and tricyclic antidepressants may increase systemic action.
special instructions
Before use, you must clean the nasal passages. Do not use for more than 5 days. During the period of use of the drug, you should observe precautions, or avoid driving and engage in other potentially hazardous activities that require high concentration of attention and quickness of psychomotor reactions.