Allergodil eye drops 0.05% 6ml
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Active ingredients
Azelastine
Release form
Drops
Composition
1 ml contains: azelastine hydrochloride 500 mcg. Auxiliary substances: hypromellose (hydroxypropylmethylcellulose), disodium edetate, benzalkonium chloride, sorbitol 70%, sodium hydroxide, water d / i.
Pharmacological effect
Histamine H1 receptor blocker, a phthalazinone derivative. It has a strong and long lasting antiallergic effect. With intraocular use, additional anti-inflammatory and membrane-stabilizing effects appear: azelastine inhibits the synthesis and release of mediators of the early and late phases of allergic reactions (including leukotriene, histamine, platelet activating factor and serotonin, reduces the number of molecular adhesion cells and eosinophils). QT interval was not detected even with prolonged use of azelastine in high doses.
Pharmacokinetics
With repeated use of Allergodil in the form of eye drops (1 drop in each eye 4 times / day), Cmax were very low and were detected at the limit or below the measurement limit.
Indications
- prevention and treatment of seasonal allergic conjunctivitis; - treatment of non-seasonal (year-round) allergic conjunctivitis.
Contraindications
- children's age up to 4 years; - hypersensitivity to azelastine or other components of the drug.
Use during pregnancy and lactation
Allergodil in the form of eye drops is not recommended for use in the first trimester of pregnancy, as well as during lactation. In experimental studies, when used in doses many times higher than the therapeutic range, no data on the teratogenic effect of azelastine was obtained.
Dosage and administration
Seasonal allergic conjunctivitis: Adults and children over 4 years old are prescribed 1 drop in each eye 2 times / day (in the morning and in the evening). If necessary, the frequency of application is increased up to 4 times / day. In the case of the anticipated exposure to an allergen, the drug is used for prophylactic purposes. Off-season (year-round) allergic conjunctivitis: adults and children 12 years and older prescribe 1 drop in each eye 2 times / day (in the morning and in the evening). If necessary, the frequency of use is increased to 4 times / day. The rules of use of the drug Allergodil1.Dry the skin around the eyes with a clean cloth. Unscrew the cap and make sure that the dropper is clean. Carefully pull down the lower eyelid. Carefully, without touching the dropper of the eyeball and mucous membrane, apply one drop of the drug in the middle of the lower eyelid.5. Lower the lower eyelid and lightly press the inner corner of the eye with your finger. Hold your finger, blink a few times. Blot the excess of the preparation with a napkin. Repeat the same for the other eye.
Side effects
On the part of the organ of vision: increased eye sensitivity, foreign body sensation, discoloration of the conjunctival membrane, irritation, soreness, itching, redness, swelling, increased tearing; rarely - dry eyes, blepharitis. Systemic reactions: dyspnea, dysgeusia, dry skin.
Overdose
Data overdose Allergodil available.
Interaction with other drugs
Drug interactions drug Allergodil not identified.
special instructions
Allergodil can be used for the treatment of infectious eye diseases as part of complex therapy (as recommended by the doctor). In case of concomitant therapy with other eye drops, they should be instilled into the eyes with an interval of at least 15 min.