More info
Active ingredients
Bee venom
Release form
Ointment
Composition
100 g of ointment contains: Active substance: bee venom 3 mg, methyl salicylate 10 g, allylisothiocyanate 1 g Supplementary substances: sodium lauryl sulphate - 700 mg, white petrolatum - 6 g, emulsified cetostearyl alcohol - 14 mg (sodium cetyl stearyl sulfate - 1.4 g, ceteostearyariums - 14 mg (sodium cetyl stearyl sulfate - 1.4 g, ceteostearyariums - 14 mg (sodium cetyl stearyl sulfate - 1.4 g, ceteostearyariums - 14 mg (1.4 g sodium cetyl stearyl sulfate - 1.4 g, cetetostearyl alcohol) - 14 mg (sodium cetyl stearyl sulfate - 1.4 g, ceteostearyariums - 14 mg 12.6 g), water - up to 100 g
Pharmacological effect
Combined preparation based on bee venom for external use. It has a local irritant effect due to the stimulation of peripheral nerve endings. It has a direct vasodilating effect, which leads to an improved supply of oxygen to tissues; accelerates the breakdown of pain-causing metabolic products. Methyl salicylate and allyl isothiocyanate cause hyperemia of the skin, have analgesic and warming effects. Apizartron helps activate metabolism, increase the elasticity of connective tissue and muscles, and decrease muscle tone. The effect develops in a few minutes after applying the drug to the affected area.
Indications
- Diseases of the musculoskeletal system (osteoarthritis, rheumatic soft tissue damage). - Arthralgia (including rheumatic diseases of the joints). - Myalgia (including those associated with overstrain. - Neuralgia (including neuritis, sciatica.). Peripheral blood circulation disorders. Pain syndrome with mild lesions of muscles, tendons, ligaments, bruises and sprains. For warming up muscles before and during sports activities.
Contraindications
- Chronic renal failure, severe. - Severe liver diseases. - Skin diseases. - Neoplasms. - Oppression of bone marrow hematopoiesis. - Mental diseases. - Acute arthritis. - Children age up to 12 years. - Increased sensitivity to bee venom, salicylates, isothiacyanates.
Use during pregnancy and lactation
It is not recommended to use the ointment Apizartron during pregnancy and lactation (breastfeeding).
Dosage and administration
Spread a strip of ointment 3–5 cm in length evenly over the skin (about 1 mm thick) until redness and heat sensation appear (2–3 min). After that, slowly and intensively rub the ointment into the skin. To enhance the therapeutic effect, it is recommended to keep the treated areas warm.Apply 2-3 times a day until the symptoms disappear (no more than 10 days). After applying Apizartron, wash hands thoroughly with soap and water.
Side effects
Allergic reactions: rarely - skin rash, itching in the area of application of the ointment.
Overdose
Data on drug overdose Apizartron not provided.
Interaction with other drugs
Drug interactions drug Apizartron is not described.
special instructions
The drug should not be applied to damaged and irritated skin, as well as to areas affected by skin disease. In patients with renal insufficiency, Apizartron should not be used on large skin surfaces for a long time. Do not allow the ointment to contact with eyes, mucous membranes and open wounds.