Aurobin ointment for rectal and external use of 20 g
Condition: New product
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Active ingredients
Prednisolone capronate + lidocaine hydrochloride + dexpanthenol
Release form
Ointment
Composition
Active ingredient: Prednisolone capronate - 0, 002 g, Lidocaine hydrochloride - 0, 020 g. Dexpanthenol - 0, 020 g. Auxiliary substances: Active ingredient concentration (g): 0, 042 g
Pharmacological effect
Pharmacological action - anti-inflammatory, analgesic, anti-allergic, local anesthetic, anti-exudative, antiseptic, regenerating.
Pharmacokinetics
Not studied
Indications
Processes involving inflammation of the perianal area, itching of the anus, eczema and dermatitis of the perianal area, fissures, hemorrhoids, anus fistula.
Contraindications
Hypersensitivity to the drug. The drug can not be used to treat the eye or periorbital area. Bacterial, viral or fungal infections of the skin. Simultaneous use of lidocaine for other indications. Children's age up to 1 year.
Precautionary measures
In the case of applying the ointment on a vast surface for a long time, it is necessary to consider the possibility of resorption of the active substances of the drug into the systemic circulation.
Use during pregnancy and lactation
There is not enough data on the safe use of the drug in pregnant women, so the drug cannot be used in the first trimester of pregnancy. In the second and third trimesters of pregnancy, when prescribing the drug, it is necessary to carefully evaluate the balance of benefits and risks. Lactation period: Corticosteroids and lidocaine penetrate into mother's milk, so during lactation it is necessary to resolve the issue of stopping breastfeeding.
Dosage and administration
Outwardly, rectally. Adults, elderly patients: Ointment is applied to the affected surface 2-4 times a day. With internal hemorrhoids, a small amount of ointment (the size of a pea) is injected into the rectum 2-4 times a day. With a decrease in symptoms, the drug can be used less frequently. The course of treatment is 5-7 days. Children: Children under 12 months should not use ointment. When using the drug in children should avoid its long-term use and on a large surface, regardless of age.
Side effects
The use of local glucocorticosteroids can primarily cause local side effects: impaired wound healing, burning sensation, itching, irritation, dryness, thinning of the skin, increased skin sensitivity. With prolonged use of glucocorticosteroids - atrophy of the skin, local hirsutism, telangiectasia, purpura, hypopigmentation, hypertrichosis, folliculitis, acne-like rashes, development of fungal infection, allergic contact dermatitis, diaper rash. When applied to large surfaces - systemic manifestations of the side effects of a glucocorticosteroid (growth retardation, Itsenko-Cushing syndrome, benign increase in intracranial pressure after treatment, hyperglycemia, glycosuria, hypokalemia, increase in blood pressure). With prolonged use and on a large surface due to the systemic action of lidocaine, bradycardia may occur.
Overdose
Acute overdose is unlikely, however, in the case of chronic overdose or improper use of the drug, symptoms may occur due to the systemic action of the glucocorticosteroid, as well as bradycardia with excessive administration of the drug in the rectum (due to lidocaine), it is necessary to stop treatment or gradually reduce the dose.
Interaction with other drugs
When using the drug locally, drug interactions are not known.
special instructions
If possible, long-term therapy should be avoided, especially in children, because of the possible suppression of adrenal function. The drug in children can be used with caution, in the minimum dose that ensures the achievement of therapeutic effect. The duration of therapy in children should not exceed 5 days. Avoid accidental contact with the eye or the periorbital area. If ingested, rinse with water. The development or spread of a secondary infection requires discontinuation of the Drug and the prescription of antimicrobial or antifungal therapy. Bacterial infection is maintained in warm, humid conditions, so the skin must be cleansed before each application of ointment. Application to a large surface or use for a long time may result in systemic absorption of the active ingredients.With prolonged use of the drug in one area, it can cause skin atrophy, especially in young individuals.