Dicloran plus gel for external use 30 g
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Active ingredients
Diclofenac
Release form
Gel
Composition
per g of gel Active substances: Diclofenac diethylamine 11.61 mg which is equivalent to diclofenac sodium 10.0 mgLNA of sown seed oil 30.0 mgLevoventol 50.0 mgMethyl salicylate 100.0 mg adjuvants: Butylhydroxyanisole 0.20 mgButylhydroxytoluene 2-2U 2U 2U 2U 2U 2U 2U 2U 2U 2U 2,22,22 mg. μl Disodium edetate 1.0 mg Dietilamine 7.1 μl Carbomer 980. 10.8 mg Lemonic acid 1.0 mg Macrogol monohydrate glyceryl hydroxystearate (Cremophor RH-40) 35.0 mg Propylene glycol 100.0 mg Water Sk. required up to 1.0 gr
Pharmacological effect
Nonsteroidal anti-inflammatory drug (NSAIDs) for external use. When used according to the instructions, DIKLORAN PLUS has a local analgesic, anti-inflammatory and anti-exudative effect. Diclofenac sodium and methyl salicylate - NSAIDs, the mechanism of action of which is due to the suppression of the synthesis of prostaglandins. When applied topically, they reduce pain and inflammation in the joints, morning stiffness and swelling of the joints, increase the range of motion. The main component of flaxseed oil is α-linolenic acid, which also has anti-inflammatory action. Levomenthol causes irritation of nerve endings, has a local distracting and mild analgesic effect, causes a feeling of coolness at the site of application of the drug.
Pharmacokinetics
When applied topically according to instructions, diclofenac sodium, methyl salicylate and linseed oil are absorbed and penetrate into the subcutaneous tissue, muscle tissue and articular capsule.
Indications
diseases of the musculoskeletal system (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis of the peripheral joints and the spine, osteochondrosis with radicular syndrome, sciatica); rheumatic lesions of soft tissues (tendovaginitis, bursitis), muscular pains of rheumatic and non-rheumatic origin (caused, including excessive physical exertion), post-traumatic inflammation of soft tissues and joints (due to sprains, overstresses and bruises).
Contraindications
Hypersensitivity to diclofenac, methyl salicylate or other components of the drug, complete or incomplete combination of bronchial asthma, recurrent polyposis of the nasal mucosa and paranasal sinuses and intolerance to acetylsalicylic acid or other nonsteroidal anti-inflammatory drugs (includinghistory), pregnancy (III trimester), lactation period (breastfeeding), children's age (up to 6 years), violation of the integrity of the skin.
Precautionary measures
For external use only. According to the instructions, DIKLORAN PLUS should be applied only to intact skin, avoiding contact with open wounds. After applying the gel should not apply an occlusive dressing. With prolonged application to open surfaces, systemic side effects may develop due to resorptive action. Do not allow the drug to enter the eyes and mucous membranes. With caution, you should prescribe the drug for severe violations of the liver and kidneys, bronchial asthma, in the I and II trimester of pregnancy, elderly patients.
Use during pregnancy and lactation
The drug is contraindicated in the III trimester of pregnancy. The question of the use of the drug in the I and II trimesters of pregnancy is solved individually. Due to the lack of experience with DICLORAN PLUS during lactation, the use of the drug in this period is not recommended.
Dosage and administration
Outwardly. Adults and children over 12 years old apply the gel to the skin 3-4 times a day and lightly rub it. The required amount of the drug depends on the size of the painful area. A single dose of the drug DIKLORAN PLUS - 2-4 g (4-8 cm with a fully open mouth of the tube). Children from 6 to 12 years old should not use more than 2 times a day, a single dose of the drug up to 2 g. The duration of treatment without consulting a doctor should not exceed 10 days. The question of the possibility of a more prolonged use of the drug the doctor decides individually and gives the patient further instructions.
Side effects
Local reactions: eczema, photosensitivity, contact dermatitis (itching, redness, swelling of the treated skin area, papules, vesicles, peeling). Systemic reactions: generalized skin rash, allergic reactions (urticaria, angioedema, bronchospastic reactions).
Overdose
When applied externally at doses recommended by the instructions to DIKLORAN PLUS, the extremely low systemic absorption of the active ingredients of the drug makes overdosing almost impossible. In case of accidental ingestion, systemic side effects may develop.Treatment with ingestion: gastric lavage, induction of vomiting, taking activated carbon, forced diuresis, symptomatic therapy. Dialysis is ineffective due to the high degree of binding of diclofenac to plasma proteins (about 99%).
Interaction with other drugs
Diclofenac may enhance the effects of drugs that cause photosensitization. Clinically significant interactions with other drugs are not described.
special instructions
If the medicinal product has fallen into disrepair or has expired Expiration date: do not throw it into sewage or on the street! Put the medicine in the bag and put it in the trash. These measures will help protect the environment!