Elkar injection for intravenous intramuscular injection of 0.1 ml 5 ml N10
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Active ingredients
Levarnitine
The brand
Elkar
Release form
Solution
Composition
Levocarnitine (carnifit) 100 mg per 1 ml. Excipients: water d / and.
Pharmacological effect
Vitamin B (vitamin BT), an amino acid derivative that is an essential cofactor of fatty acid metabolism. Normalizes protein and fat metabolism. It has an anabolic effect. Contributes to the normalization of the main metabolism in hyperthyroidism.
Pharmacokinetics
When ingestion is well absorbed. Cmax is reached after 3 hours, the therapeutic concentration is maintained for 9 hours. When i / m administration is detected in plasma for 4 h. After i / v administration, it disappears from the blood after 3 h. Easily penetrates the liver and myocardium, more slowly - into the muscles. Excreted by the kidneys mainly in the form of acyl esters.
Indications
Micro-pediatrics and pediatrics: hypotrophy, hypotension, weakness, effects of birth trauma and asphyxia, conditions after serious diseases and operations. Psychiatry and neurology: neurogenic anorexia, physical exhaustion, traumatic encephalopathy. Gastroenterology: chronic gastritis with reduced secretory function, chronic pancreatitis with reduced exocrine function. Endocrinology: growth retardation in children under 16 years of age, mild forms of thyrotoxicosis. Dermatology: psoriasis, seborrheic eczema, scleroderma.
Contraindications
Hypersensitivity to left carnitine.
Dosage and administration
Is ingested. Doses and duration of treatment are set individually, depending on the evidence.
Side effects
Possible: nausea, vomiting, diarrhea, abdominal pain, allergic reactions, muscle weakness (in patients with uremia); with the rapid introduction (80 drops / min or more), pain may occur along the vein, passing with a decrease in the rate of administration. Seldom: a specific smell from a body.
Interaction with other drugs
With the simultaneous use of anabolics enhance the effect of left carnitine. With simultaneous use of GCS contribute to the accumulation of left carnitine in the tissues (except the liver).
special instructions
The possibility of using levocarnitine for the treatment of mitochondrial myopathy caused by zidovudine is currently being studied.