Erythromycin topical ointment 15 g
Condition: New product
1000 Items
Rating:
Be the first to write a review!
More info
Description
Erythromycin ointment is used as an antibiotic for external use. It has a bacteriostatic effect. However, in high doses in relation to sensitive microorganisms has a bactericidal effect.
Active ingredients
Erythromycin
Release form
Ointment
Pharmacological effect
An antibiotic group macrolides. It has a bacteriostatic effect. However, in high doses in relation to sensitive microorganisms has a bactericidal effect. Erythromycin reversibly binds to the ribosomes of bacteria, thereby inhibiting protein synthesis. Active against gram-positive bacteria: Staphylococcus spp. (strains producing and not producing penicillinase), Streptococcus spp. (including Streptococcus pneumoniae), Gram-negative bacteria: Neisseria gonorrhoeae, chambers, chambers, chaste, Permussis, Brucella spp. , Chlamydia spp., Spirochaetaceae, Rickettsia spp. Gram-negative rods are resistant to erythromycin, incl. Escherichia coli, Pseudomonas aeruginosa, Shigella spp., Salmonella spp.
Pharmacokinetics
Bioavailability is 30-65%. Distributed in most tissues and body fluids. Plasma protein binding is 70-90%. Metabolized in the liver, partly with the formation of inactive metabolites. T1 / 2 - 1.4-2 hours. Derived from the bile and urine.
Indications
Infectious and inflammatory diseases caused by microorganisms susceptible to erythromycin, including diphtheria, whooping cough, trachoma, brucellosis, legionnaires' disease, tonsillitis, scarlet fever, otitis media, sinusitis, cholecystitis, pneumonia, gonorrhea, syphilis. Treatment of infectious and inflammatory diseases caused by pathogens (in particular, staphylococcus) resistant to penicillin, tetracyclines, chloramphenicol, streptomycin.
Dosage and administration
Set individually depending on the location and severity of the infection, the sensitivity of the pathogen. In adults, they are used in a daily dose of 1–4 g. For children under the age of 3 months, 20–40 mg / kg / day, at the age of 4 months to 18 years, 30–50 mg / kg / day. Frequency of use - 4 times / day. The course of treatment is 5-14 days, after the disappearance of the symptoms, the treatment is continued for another 2 days. It is taken 1 hour before a meal or 2-3 hours after a meal. Lubricate the affected skin with a solution for external use. Ointment is applied to the affected area, and in case of eye diseases, it is laid behind the lower eyelid. The dose, frequency and duration of use is determined individually.