More info
Active ingredients
Phospholipids
Release form
Capsules
Composition
Active ingredient: Methionine + Phospholipids polyunsaturated from soy lecithin Concentration of active ingredient (mg): Methionine 100 mg, polyunsaturated phospholipids from soy lecithin (lipid PPL-400) 300 mg
Pharmacological effect
The combined drug, has a hepatoprotective effect, normalizes all types of metabolism (fat, protein, carbohydrate). Methionine, one of the active components of the drug, is an essential amino acid that is a source of mobile methyl groups. Methionine is required for choline synthesis. An increase in the choline content contributes to an increase in the synthesis of endogenous (internal) phospholipids and a decrease in the deposition of neutral fat in the liver. Methionine is also required for the disposal of xenobiotics. When atherosclerosis reduces the concentration of cholesterol and increases the concentration of blood phospholipids. Essential phospholipids are indispensable factors for the development and functioning of liver cells. The main fraction of essential phospholipids in the preparation is represented by phosphatidylcholine (73%), which is the main component of biological membranes. Once in the body, phosphatidylcholine restores the integrity of the membranes of the affected liver cells and activates the phospholipid-dependent enzymes located in the membrane, normalizing permeability and enhancing the detoxification and excretory potential of the liver cells. the functional state of the liver cells and have a hepatoprotective effect. Methionine is also involved in metabolism with Eros-containing amino acids, in the synthesis of epinephrine, creatinine and other biologically active compounds, converts the action of hormones, vitamins (B12, ascorbic, folic acids), enzymes, proteins, participates in peremetylirovaniya, deamination, decarboxylation reactions. and also normalizes fat, carbohydrate and protein metabolism in the body.
Pharmacokinetics
Data on the pharmacokinetics of the drug Eslidin not provided.
Indications
The drug is used in gastroenterology, dermatology, neurology, cardiology.– fatty liver dystrophy of various etiologies; - acute and chronic hepatitis (except viral); - liver cirrhosis; - toxic liver damage (alcoholic, narcotic, medicinal); complication of other diseases); - pre- and postoperative treatment for operations in the hepatobiliary zone; - psoriasis (as part of complex therapy); - cerebral arteriosclerosis (as part of complex therapy); - teroskleroz coronary arteries (in the complex therapy); - diabetes (in the complex therapy); - depletion dystrophy.
Contraindications
Severe liver failure, hepatic encephalopathy; - viral hepatitis; - children under 3 years of age; - hypersensitivity to the components of the preparation.
Precautionary measures
The drug should be used with caution during pregnancy, in children aged 3 to 7 years, with renal failure (due to the risk of hyperazotemia).
Use during pregnancy and lactation
Studies confirming the safety of Eslidine for the fetus and safety for the child during breastfeeding have not been carried out. Use of the drug during pregnancy and lactation is possible only by a doctor's prescription in cases where the intended benefits to the mother outweigh the possible risk to the fetus and child.
Dosage and administration
The drug is taken orally during meals. Capsules should be swallowed whole with a sufficient amount of water. In liver diseases, atherosclerosis of the coronary arteries and brain vessels, diabetes mellitus, dystrophy and exhaustion, 2 capsules are prescribed 3 times / day. The recommended course of treatment is 3 months, the minimum course is 1 month. In psoriasis, 2 capsules, 3 times / day. The recommended course of treatment is 2 weeks. Children over 7 years with liver diseases, diabetes, and fatty liver - 2 capsules 3 times / day for 1-3 months. In psoriasis, children over 7 years old - 2 capsules 3 times / day within 2 weeks. Children from 3 to 7 years old are prescribed 1 capsule 3 times / day for 1-3 months.
Side effects
Allergic reactions are possible.
Overdose
If the daily dose is accidentally exceeded several times, a decrease in blood pressure, an increase in heart rate, and disorientation are possible. Treatment: Symptomatic therapy is carried out.
Interaction with other drugs
Drug interaction of the drug Eslidin is not described.
special instructions
With caution should use the drug for renal failure (due to the risk of increasing hyperazotemia).