Femoston pills 110 28 pieces
Condition: New product
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Active ingredients
Didrogesterone + Estradiol
Release form
Pills
Composition
Active ingredient: dydrogesterone (dydrogesterone) estradiol (estradiol) Concentration of the active substance (unit): estradiol hemihydrate 1.03 mg, didrogesterone 5 mg
Pharmacological effect
Estrogen-progestin.
Indications
hormone replacement therapy for estrogen deficiency disorders in postmenopausal women; prevention of postmenopausal osteoporosis in women with a high risk of fractures with intolerance or contraindications to the use of other drugs.
Contraindications
established or suspected pregnancy and lactation; diagnosed or suspected breast cancer, a history of breast cancer; diagnosed or suspected progestogen-dependent neoplasms; diagnosed or suspected estrogen-dependent malignant tumors, including endometrial cancer, including in the anamnesis; bleeding from the vagina of unknown etiology; thromboembolic disease at present or in history (for example: myocardial infarction, deep vein thrombosis, pulmonary embolism); violation of cerebral circulation; acute or chronic liver disease now or in history (before normalization of laboratory parameters of liver function); untreated endometrial hyperplasia; porphyria; hypersensitivity to the drug; galactose intolerance, lactase deficiency, glucose malabsorption syndrome, galactose. With caution: uterine leiomyoma, endometriosis; the presence of risk factors for the emergence of estrogen-dependent tumors (for example, the first degree of heredity of breast cancer); liver adenoma; cholelithiasis; migraine or intense headache; renal failure; bronchial asthma; endometrial hyperplasia in history; epilepsy; otosclerosis; multiple sclerosis; hemoglobinopathies; risk factors for thromboembolic states, incl. angina pectoris, prolonged immobilization, severe obesity (body mass index more than 30 kg / m2); arterial hypertension; diabetes mellitus, both in the presence of vascular complications and in cases of their absence; systemic lupus erythematosus.
Dosage and administration
the drug is taken orally in continuous mode, 1 tablet per day. The duration of therapy is determined by the ratio of the benefits and risks to the health of a woman and the severity of estrogen deficiency. Prevention of postmenopausal osteoporosis should be carried out taking into account the individual tolerance of the drug and possible effects on bone mass, which are dose-dependent.
Side effects
headache, migraine; nausea, abdominal pain, flatulence; tension / tenderness of the mammary glands, metrorrhage in the first months of treatment, spotting from the vagina, pain in the lower abdomen; cramps in the muscles of the lower extremities; asthenia; increase or decrease in body weight.