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Active ingredients
Ofloxacin
Release form
Drops
Composition
Active ingredient: Ofloxacin Concentration of active ingredient (mg): 3 mg
Pharmacological effect
Antimicrobial broad-spectrum drug from the group of fluoroquinolones for local use in ophthalmology. The bactericidal action of ofloxacin is associated with the blockade of the DNA gyrase enzyme in bacterial cells. It is highly active against most Gram-negative microorganisms: Esherichia coli, Salmonella spp., Proteus spp., Morganella morganii, Shigella spp., Klebsiella spp., Ibrahimla morganella morganii, Shigella spp., Ibrahim morph, etc. , Citrobacter spp., Yersinia spp., Providencia spp., Haemophilus influenzae, Neowseria gonorrhoeae, Neisseria gonorrhoeae, Neisseria meningitidis, Mycoplasma spp., Legionella pneumophila, Acinetobacter spp., Chlamydia spp. Spp. Moderately sensitive to ofloxacin Enterococcus faecalis, Streptococcus pneumoniae, Pseudomonas spp. To ofloxacin microorganisms producing β-lactamazu are sensitive. Anaerobic bacteria are insensitive to the preparation (except for Bacteroides urealyticus).
Pharmacokinetics
When applied topically, a therapeutic concentration of the drug in the eye tissue is achieved.
Indications
Infectious and inflammatory diseases of the anterior part of the eye caused by microorganisms sensitive to ofloxacin, blepharitis, barley, conjunctivitis, dacryocystitis, keratitis, corneal ulcer, chlamydial eye infection, prevention and treatment of bacterial infection after eye injuries and surgical procedures.
Contraindications
Hypersensitivity to the drug components, pregnancy, lactation.
Precautionary measures
During the use of the drug is not recommended to wear contact lenses.
Use during pregnancy and lactation
Data on the negative effects of ofloxacin on the fetus are not available, however, the drug is contraindicated for use during pregnancy and lactation (breastfeeding).
Dosage and administration
Drops The drug is instilled in 1 drop in the conjunctival sac of the sore eye 2-4 times a day. It is not recommended to use the drug for more than 2 weeks. With the simultaneous use of more than one drug, it is necessary to observe the minimum 5-minute interval between installations. An ointment of 1.5 cm strips of ointment is placed in the lower eyelid of the sore eye 2-3 times a day, in the case of chlamydial infection - 5 times a day. It is not recommended to use the drug for more than 2 weeks. Perhaps a combination of eye drops and ointment Floxal. With the simultaneous use of more than one drug ointment should be used last.
Side effects
Allergic reactions; transient conjunctival hyperemia, burning sensation; discomfort in the eyes, itching and dryness of the conjunctiva, photophobia, lacrimation, rarely - dizziness.
Overdose
Data overdose Floxal no.
Interaction with other drugs
Drug interaction drug Floxal not described.
special instructions
Sunglasses should be worn (due to the possible development of photophobia) and long exposure to bright light should be avoided. Impact on the ability to drive vehicles and control mechanisms After applying the ointment, visual acuity temporarily worsens, which must be considered when driving a car and working with mechanisms.