Galazolin gel nasal 0.05% 10g
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Active ingredients
Xylometazoline
Release form
Gel
Composition
In 1 gram of gel: Xylometazoline hydrochloride 0.5 mg. Excipients: sodium dihydrogen phosphate monohydrate - 3.68 mg, sodium hydrogen phosphate dodecahydrate - 2.5 mg, sodium chloride - 3.3 mg, sorbitol - 20 mg, disodium edetate - 0.2 mg, benzalkonium chloride (50% solution) - 0.2 mg, hyatellose - 14 mg, glycerol - 40 mg, purified water - up to 1 g.
Pharmacological effect
Vasoconstrictor drug for local use in ENT practice. Alpha-adrenomimetik from the group of imidazole derivatives. In low concentrations acts on? 2 -adrenoreceptors, in high concentrations has an effect on? 1 -adrenoreceptors. When applied topically, it causes narrowing of the blood vessels, which leads to a decrease in edema and hyperemia of the mucous membranes of the nasopharynx, reduces the amount of nasal secretions, and facilitates nasal breathing in rhinitis. The action of the drug begins after 5-10 minutes and lasts for 5-6 hours when used in the form of nasal drops and for 10 hours when used in the form of a nasal gel.
Indications
Acute rhinitis of viral or bacterial origin. - Allergic rhinitis. - acute sinusitis. - chronic sinusitis in the acute phase. - pollinosis. - otitis media (in order to reduce swelling of the mucous membrane of the nasopharynx and restore the patency of the Eustachian tube).
Contraindications
Hypersensitivity to the drug. - atrophic rhinitis. - angle-closure glaucoma. - arterial hypertension . - pronounced atherosclerosis. - tachycardia. - hyperthyroidism (for nasal drops). - surgery on the meninges (in history). - simultaneous administration of MAO inhibitors and a period of 14 days after the end of their use. - simultaneous administration of tricyclic antidepressants. - pregnancy. - children's age up to 6 years (for 0.1% nasal drops) and up to 2 years (for 0.05% nasal drops). - children's age up to 12 years (for 0.1% nasal gel) and up to 3 years (for 0.05% nasal gel).
Use during pregnancy and lactation
Contraindicated in pregnancy. Data on the allocation of xylometazoline with breast milk is not available. It is necessary to carefully prescribe the drug to women during lactation (breastfeeding).
Dosage and administration
Galazolin. in the form of a nasal gel 0.05%: for children aged 3 to 12 years on average, 1 injection in each nostril every 8-10 hours. When administered with a dispenser, 1 dose of 0.05% nasal gel contains 50 mcg xylometazoline. Galazolin. in the form of a nasal gel 0.1%: for adults and children over 12 years old, on average, 1 injection into each nostril every 8-10 hours. When administered with a dosing device, 1 dose of 0.1% nasal gel contains 100 mcg xylometazoline. Before using the nasal gel, each time it is necessary to remove the nozzle, then press the dispenser 3-5 times until the gel appears. Do not exceed the indicated dose. The course of treatment is no more than 3-5 days. The maximum duration of use is 2 weeks.
Side effects
Local reactions: with frequent and / or long-term use - irritation and / or dryness of the nasal mucosa, burning and paresthesia of the nasal mucosa, sneezing, hypersecretion of the nasal mucosa. rarely - swelling of the mucous membrane of the nasal cavity. Systemic reactions: rarely - palpitations, tachycardia, palpitation, arrhythmia, increased blood pressure (especially in patients with diseases of the cardiovascular system), headache, nausea, vomiting, insomnia, weakness, fatigue, drowsiness, blurred vision, allergic reactions (asphyxiation, vasomotor edema). with long-term use and / or when used in high doses - depression, medical rhinitis.
special instructions
Local reactions: with frequent and / or long-term use - irritation and / or dryness of the nasal mucosa, burning and paresthesia of the nasal mucosa, sneezing, hypersecretion of the nasal mucosa. rarely - swelling of the mucous membrane of the nasal cavity. Systemic reactions: rarely - palpitations, tachycardia, palpitation, arrhythmia, increased blood pressure (especially in patients with diseases of the cardiovascular system), headache, nausea, vomiting, insomnia, weakness, fatigue, drowsiness, blurred vision, allergic reactions (asphyxiation, vasomotor edema). with long-term use and / or when used in high doses - depression, medical rhinitis.