Glitselaks rectal suppositories for adults 1.5g N10
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Active ingredients
Glycerol
Release form
Suppositories
Composition
1 ml of oral solution contains niketamida 250 mg, water for injection up to 1 ml;
Pharmacological effect
When inserted into the rectum, candles exert a slight irritating effect on the mucous membrane and, by reflex, gently stimulate the contractile activity of the intestine, causing a laxative effect. Glycerol suppositories also contribute to the softening of the fecal masses and their passage through the colon, especially with atonic constipation, in which the act of defecation is carried out with great difficulty and often very painful;
Pharmacokinetics
Glycerin is rapidly and almost completely absorbed from the mucous membrane of the rectum. Actively metabolized in the liver. It is one of the substrates for gluconeogenesis and increases the content of glucose in the blood plasma. With urine in unchanged form, 7-14% is excreted. ;
Indications
Constipation of various origins - functional, psychogenic, age-related (including rectal coprostasis in people of old and old age), with limited mobility, pregnancy and breastfeeding, etc .; prevention of constipation in patients who can not strain during bowel movements, including with painful, thrombosed hemorrhoids, perianal abscess, anorectal stenosis, after myocardial infarction; for softening the skin and treating mucous membranes (liquid). ;
Contraindications
Hypersensitivity, renal failure, appendicitis, bleeding, diarrhea, hemorrhoids in the acute stage, anal fissures, inflammatory diseases and rectal tumors.
Use during pregnancy and lactation
Pregnant women should not use the drug, because of the risk of reflex stimulation of the uterus. During lactation, the use of Glitselaks is possible only after consulting a doctor;
Dosage and administration
Dosage and administration
:; Enter into the rectum one candle 1 time per day, preferably 15-20 minutes after breakfast. ;Side effects
During therapy, local (in the form of itching and burning skin) and allergic reactions may develop. ;
Overdose
No data ;
Interaction with other drugs
There is no data on the interaction of Glitselaks with other drugs;
special instructions
Regular use as a laxative is not recommended. With systemic use in dehydrated patients, as well as in the presence of diabetes mellitus, the risk of developing severe dehydration symptoms, leading to vascular overload and, accordingly, hyperglycemia, increases. A non-concreted hyperglycemic coma (when used orally) is quite rare, but it should be borne in mind that several deaths have been reported;