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Active ingredients
Dextrose
Release form
Pills
Composition
Active ingredient: dextrose; Auxiliary substance: talc, stearic acid; Concentration of active ingredient (mg): 500 mg
Pharmacological effect
Means for rehydration and detoxification .; Isotonic dextrose solution (5%) is used to replenish the body with fluid. In addition, it is a source of valuable nutrient that is easily digested. The metabolism of glucose in the tissues produces a significant amount of energy necessary for the vital activity of the body .; With the on / in the introduction of hypertonic solutions (10%, 20%, 40%), the osmotic pressure of the blood increases, the flow of fluid from the tissues into the blood increases, metabolic processes increase, the antitoxic function of the liver improves, the contractile activity of the heart muscle increases, the vessels expand, and diuresis.
Pharmacokinetics
Dextrose, entering the tissue, is phosphorylated, turning into glucose-6-phosphate, which is actively involved in many parts of the body's metabolism. Excreted by the kidneys.
Indications
Hypoglycemia; carbohydrate deficiency.
Contraindications
Diabetes mellitus (except in cases of hypoglycemia).
Use during pregnancy and lactation
Perhaps the use of dextrose during pregnancy and lactation (breastfeeding) according to indications.
Dosage and administration
Glucose pills are taken orally in 0.5 - 2.5 - 5 g (1-10 pills) at the reception, the pills can be crushed, chewed, or dissolve. If necessary, the dose may be increased .; Repeated administration is possible taking into account body weight, not exceeding the dose of 0.3 g / kg / h; Take the pill should be 1-1.5 hours before meals due to a possible decrease in appetite after taking glucose.
Side effects
Decreased appetite, hyperglycemia (with diabetes or overdose).
Overdose
Currently, no cases of overdose have been reported.
Interaction with other drugs
No data provided.
special instructions
With caution, dextrose is prescribed for decompensated heart failure, chronic renal failure (oligoanuria), and hyponatremia .; To increase the osmolarity of 5% dextrose solution can be combined with an isotonic solution of sodium chloride.