Hexoral solution for topical administration 0.1% 200 ml
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Active ingredients
Hexaetine
The brand
Hexoral
Release form
Solution
Composition
Active ingredient: Hexidine Concentration of active ingredient (%): 0.1%
Pharmacological effect
Antiseptic agent. The antimicrobial effect of the drug Hexoral is associated with the suppression of oxidative reactions of bacteria metabolism (thiamine antagonist). The drug has a broad spectrum of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida, but hexoral may also have an effect in the treatment of infections caused by, for example, pseudomonas aeruginosa or proteus. at a concentration of 100 mg / ml, the drug inhibits most strains of bacteria. development of resistance was not observed. the drug has an antiviral effect against influenza a viruses, respiratory syncytial virus (pc-virus), herpes simplex virus type 1, affecting the respiratory tract. hexatidine has a weak anesthetic effect on the mucous membrane.
Pharmacokinetics
Hexetidine adheres very well to the mucous membrane and is practically not absorbed. After a single application of the drug, traces of the active substance are found on the mucous membrane of the gums for 65 hours. In dental plaque, active concentrations persist for 10-14 hours after application.
Indications
Inflammatory and infectious diseases of the oral cavity and pharynx. In the complex treatment of severe febrile or purulent diseases of the oral cavity and pharynx, requiring the prescription of antibiotics and sulfonamides, tonsillitis. Angina (including sore throats with lesions of the lateral cushions, Plagin-Vincent angina). Pharyngitis.Gingivitis and bleeding gums. Periodontal diseases (periodontal diseases and their symptoms. Stomatitis (inflammation of the oral mucosa), glossitis (inflammation of the tongue), aphthous ulcers (painful inflammation with superficial tissue defects ) in order to prevent superinfections. Alveolar infection (tooth holes) after tooth extraction. Fungal infections of the oral cavity and pharynx, especially candidal stomatitis (thrush). Before and after operations in the oral cavity and pharynx. Additional oral hygiene in case of common diseases. Elimination of unpleasant bad breath, especially in the case of collapsing tumors of the oral cavity and pharynx. An adjuvant in the treatment of colds.
Contraindications
Children's age up to 3 years; hypersensitivity to the drug.
Precautionary measures
The drug should be stored out of the reach of children at a temperature not higher than 25 ° C.
Use during pregnancy and lactation
Information about any undesirable effects when using the drug Geksoral during pregnancy and during breastfeeding is not. However, before prescribing Hexoral to pregnant or lactating women, the doctor should carefully weigh the expected benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placental barrier and secretion of breast milk.
Dosage and administration
Adults and children over 3 years old: apply topically in the form of mouth and throat rinsing for at least 30 seconds with 15 ml of undiluted solution. Unless otherwise indicated, apply 2 times / day, preferably in the morning and in the evening. Hexethidine adheres to the mucous membrane and due to this gives a lasting effect. In this regard, the drug should be used after meals. Geksoral is also safe for more frequent use. The duration of treatment is determined by the doctor. Do not use in children under 3 years of age. Hexoral is a solution for topical use only for rinsing the mouth and throat. The solution can not be swallowed. For rinsing, you must always use the undiluted solution. When treating diseases of the oral cavity, the preparation can also be applied with a tampon.
Side effects
In some cases: hypersensitivity reactions to the drug. With long-term use: a violation of taste is possible.
Overdose
It is unlikely that hexethidine can have a toxic effect when used in recommended doses. Symptoms: ingestion of a large amount of hexethidine solution containing ethanol can lead to the appearance of signs / symptoms of alcohol intoxication. Treatment: symptomatic therapy, as with alcohol intoxication. Gastric lavage is necessary within 2 hours after ingesting an excess dose. In any cases of overdose, the patient should immediately consult with a physician.
Interaction with other drugs
Drug interaction of the drug Hexoral is not described.
special instructions
Geksoral solution for topical use can be used for rinsing the mouth and throat only in the caseif the patient can spit out the solution after rinsing. Hexoral solution for topical use contains ethanol 96% (4.3333 g / 100 ml of solution). The patient should be informed that if the drug has become unusable or the shelf life has expired water or throw it out. It is necessary to put the drug in the bag and put it in the trash. These measures will help to protect the environment. Use in pediatrics In children, the drug can be used from an age when there is no danger of uncontrolled ingestion when using the solution. The effect on the ability to drive vehicles and control mechanisms performing other potentially hazardous activities.