Ismigen pills lingual 7mg N10
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Active ingredients
Bacteria lysate [Esheriсhia сoli]
Release form
Pills
Composition
Bacteria lysates, incl. staphylococcus aureus, streptococcus pyogenes, streptococcus viridans, streptococcus pneumoniae (types - ty1 / eq11, ty2 / eq22, ty3 / eq14, ty5 / eq15, ty8 / eq23, ty47 / eq24), klebsiella pneumonia, which you need to use, which you need to use, which you need to use, which you need to use, which you need to use, which you need to use, which you need to use. catarrhalis 7 mg.
Pharmacological effect
Combined immunostimulating drug of bacterial origin for sublingual (sublingual) use. It is a polyvalent antigen complex, which includes lysates of bacteria - the most common pathogens of respiratory infections. The lysates that make up the Immigene are obtained by mechanical action. Ismigen, like other immunostimulants of bacterial origin of the second generation, has a nonspecific immunostimulating and specific vaccine effect. The imimigen sublingual pills have an effect on various parts of the immunity. Stimulates both the local cellular and humoral immune response and the systemic immune response. It activates phagocytosis, increases the content of lysozyme in saliva, promotes an increase in the number of immunocompetent cells. Increases the functional and metabolic activity of macrophages (including alveolar) and polymorphonuclear leukocytes. It activates the processes of peroxidation and the expression of adhesion molecules on macrophage monocyte cells and granulocytes LEA-1, MAC-1, p-150, ICAT-1, which ensures cooperation with T-lymphocytes and antigen-presenting cells and contributes to the destruction of infectious agents. Stimulates the secretion of macrophage monocyte prostaglandin E2 cells, activates natural killer cells; stimulates the release of anti-inflammatory cytokines - interleukin IL-1, IL-2, IL-6, IL-8, gamma-interferon, tumor necrosis factor alpha; inhibits the synthesis of IL-4, IL-12; increases the concentration of secretory immunoglobulin IgA in saliva, serum IgA, IgG, IgM; reduces the concentration of serum IgE. As a result of treatment with Ismigen, the frequency, severity and duration of acute infections of the respiratory tract are reduced; there is relief and alleviation of symptoms such as fever, cough, shortness of breath, decreases the need for antibacterial and anti-inflammatory therapy; in patients with chronic diseases of the respiratory tract, the drug also prevents exacerbations.
Pharmacokinetics
Data on the pharmacokinetics of the drug is not provided.
Indications
Acute and subacute infections of the upper and lower respiratory tract: bronchitis, tonsillitis, pharyngitis, laryngitis, rhinitis, sinusitis, otitis, including complications from the flu (treatment as part of combination therapy). Recurrent infections of the upper and lower respiratory tract, chronic bronchitis (prevention of exacerbations) .
Contraindications
Hypersensitivity to the active and / or auxiliary components of the drug, pregnancy, lactation, children under 3 years
Precautionary measures
Do not exceed recommended doses.
Use during pregnancy and lactation
Contraindicated.
Dosage and administration
Under the tongue; take on an empty stomach. The tablet should be kept under the tongue until completely dissolved. Sublingual pills should not be absorbed, chewed or swallowed. Acute and subacute infections of the upper and lower respiratory tractPatient 1 tablet per day until the symptoms of the disease disappear (at least 10 days). Recurrent infections of the upper and lower respiratory tract, prevention of exacerbations of chronic respiratory diseases 1 tablet per day for 10 days. The prophylactic course includes three cycles of 10 days each with 20-day intervals between them. The prophylactic course should be given no more than 1-2 times a year. When you skip the next dose, you should not double it the next time you take it.
Side effects
The frequency of side effects is classified according to the recommendations of the World Health Organization: very often - more than 10%; often more than 1 and less than 10%; infrequently - more than 0.1 and less than 1%; rarely more than 0.01 and less than 0.1%; very rarely - less than 0.01%. From the side of the skin: very rarely - urticaria, impetiginous dermatitis, folliculitis. Others: very rarely - inflammation of the salivary gland, acute laryngitis, rhinitis.
Overdose
Information about cases of overdose are absent.
Interaction with other drugs
Ismigen can be used simultaneously with other drugs intended for the treatment of acute and chronic respiratory diseases. The specific features of the interaction of Emigrant with other drugs have not yet been described.
special instructions
Children between 3 and 6 years of age should be monitored by adults every day, until the tablet completely dissolves in the mouth. The effect on the ability to drive and control machinery is not affected.