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Active ingredients
Allantoin + Heparin Sodium + Onion Bulbs Extract
Release form
Gel
Composition
Active ingredient: liquid extract of onion, heparin sodium, allantoin Concentration of active ingredient: liquid extract of onion 100 mg, heparin sodium 50 IU, allantoin 10 mg
Pharmacological effect
Combined drug, the action of which is due to the properties of its constituent components. It has a fibrinolytic, anti-inflammatory (due to an extract of Seraye bulbs), an antithrombotic (due to heparin), and a keratolytic effect (due to allantoin). Stimulates cell regeneration without hyperplasia. Inhibits the proliferation of keloid fibroblasts.
Pharmacokinetics
The experiment showed that heparin penetrates the connective tissue of the dermis in a clinically sufficient amount over 4 hours. Deep penetration is provided by a combination of heparin with an extract of Cerae bulbs and allantoin (transepidermal heparinization). When using the drug Contractubex systemic absorption is not observed.
Indications
Combined drug, the action of which is due to the properties of its constituent components. It has a fibrinolytic, anti-inflammatory (due to an extract of Seraye bulbs), an antithrombotic (due to heparin), and a keratolytic effect (due to allantoin). Stimulates cell regeneration without hyperplasia. Inhibits the proliferation of keloid fibroblasts.
Contraindications
hypersensitivity to the drug.
Precautionary measures
Do not exceed recommended doses.
Use during pregnancy and lactation
The effect of the drug during pregnancy and lactation has not been studied.
Dosage and administration
The consumption of the drug in one application on average 0.5 cm of gel per cicatricial surface of 20-25 cm2. Apply 2-3 times / day, easily rubbing into the scar tissue. The course of treatment for fresh scars averages 4 weeks. In case of long-standing dense scars, an occlusive bandage with a gel is applied at night. The course of treatment is on average 3-6 months. In case of Dupuytren's contracture, the course of treatment is an average of 12 months. For prevention, a phase is used after epithelialization of the wound (no granulation is applied).
Side effects
Seldom: local skin reactions.
Overdose
An overdose of the drug Contractubex not described.
Interaction with other drugs
Drug interactions drug Contractubex not described.
special instructions
To enhance the effect of the drug should be applied to the pre-steamed skin. May be used in combination with physiotherapeutic measures. When treating fresh scars, ultraviolet radiation, exposure to cold and intensive massage should be avoided.