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Active ingredients
Ibuprofen
Release form
Cream
Composition
Active ingredient: Ibuprofen (Ibuprophenum). Concentration of active ingredient (mg): 5 g
Pharmacological effect
Dolgit cream is a highly active remedy for external treatment of rheumatic and non-rheumatic pain at the level of the body's motor system. Since ibuprofen being the active principle is dissolved in the base of the cream, it is quickly absorbed by the skin and thus quickly enters the affected parts of the tissues. Dolgit cream has analgesic and anti-inflammatory effects; swelling is reduced, and mobility clearly improves. Dolgit cream is well tolerated by the skin, it is easy to apply and it has a pleasant smell.
Pharmacokinetics
When applying the cream / gel on the skin, ibuprofen penetrates into deeper tissues (subcutaneous tissue, muscles, joints, synovial fluid) and reaches therapeutic concentrations in them. The therapeutic effect in the application area is achieved by direct distribution through the skin in the target tissue. In small quantities is determined in the blood plasma. With the recommended method of application, the concentration in synovial fluid is about 2 μg / ml.
Indications
Inflammatory and degenerative diseases of the musculoskeletal system: articular syndrome with exacerbation of gout, arthritis (rheumatoid, psoriatic, gouty), scleuroleopathic periarthritis, ankylosing spondylitis (ankylosing spondylitis, deforming osteoarthritis, osteochondrosis with a coronary syndrome, and only 8). lumbago, sciatica, muscle pain (myalgia) of rheumatic and non-rheumatic origin, injuries (sports, industrial, domestic, etc.) without compromising the integrity of the skin (dislocated and stretching or tearing of the ligaments and muscles, bruises, post-traumatic soft tissue swelling and t.).
Contraindications
Hypersensitivity to ibuprofen, components of the drug and other NSAIDs, moist dermatosis, eczema, skin integrity problems (including infected abrasions and wounds) at the site of application of the cream. pregnancy, lactation. children's age up to 14 years.
Precautionary measures
Ointment should not be used to treat open wounds infected with the infection.It is important to avoid getting the drug in the eyes, mouth, and mucous membranes. If for a period of ten days Dolgit does not have the proper pharmacological action, it is necessary to consult a doctor. The use of ointment for children under 12 years is possible only after consulting with a specialist. The drug does not reduce attentiveness and does not affect the coordination of movements. Thus, Dolgit can be used by drivers and other patients whose profession requires concentration and a high reaction rate.
Use during pregnancy and lactation
1-And trimester of pregnancy and lactation is contraindicated
Dosage and administration
Outwardly The cream is applied to the skin in the area of the painful area 3-4 times a day and rubbed with light movements until complete absorption of the drug. A strip of cream 4-10 cm long is used depending on the area of the affected surface. The duration of treatment depends on the severity of the disease and the nature of the damage, and is, on average, 2-3 weeks.
Side effects
Usually the drug is well tolerated. In rare cases, there may be temporary signs of local irritation of the skin in the form of redness, swelling, rashes, itching of the skin, burning sensation and tingling. In the case of hypersensitivity to NSAIDs possible phenomena of bronchospasm. With prolonged use of the drug in particularly sensitive patients may develop systemic side effects.
Overdose
Cases of overdose of cream or gel are not described. Treatment: In case of accidental ingestion, it is necessary to clear the stomach (induce vomiting, prescribe activated charcoal) and consult a doctor. Further treatment, if necessary, symptomatic.
Interaction with other drugs
Cream. You should consult with your doctor before using the drug, if you use any other drugs. Gel. Drug interactions with other drugs are not described. However, it should be borne in mind that even with topical administration, ibuprofen has a systemic effect and, theoretically, side effects may increase if used simultaneously with other NSAIDs.
special instructions
In severe cases, the combined use of a cream or gel is recommended externally with the intake of other dosage forms of NSAIDs (parenterally, orally, rectally).Avoid getting the cream or gel in the eyes and on other mucous membranes. Influence on the ability to drive vehicles or perform work that requires increased speed of physical and mental reactions. The use of the drug does not affect the ability to engage in activities requiring increased attention, motor coordination, high speed mental and physical reactions (for example, driving, working with complex mechanisms, etc.).