Nazivin sensitive spray nasal 22.5 μg dose 10ml
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Active ingredients
Oxymetazoline
Release form
Spray
Composition
Active ingredient: Oxymetazoline Auxiliary substances: citric acid monohydrate 0.609 mg, sodium citrate dihydrate 3.823 mg, glycerol (85%) 24.921 mg, purified water 978.147 mg. Concentration of active substance (mg): 0.500 mg
Pharmacological effect
Vasoconstrictor drug for local use. When applied to the inflamed mucous membrane of the nasal cavity reduces its swelling and nasal discharge. Restores nasal breathing. Elimination of edema of the mucous membrane of the nasal cavity helps to restore aeration of the paranasal sinuses of the nasal cavity, middle ear cavity, which reduces the likelihood of bacterial complications (sinusitis, sinusitis, otitis media). With local intranasal use in therapeutic concentrations, it does not irritate and does not cause hyperemia of the nasal mucosa. With local intranasal use, oxymetazoline does not have a systemic effect. Oxymetazoline starts to act quickly, within a few minutes. The duration of the drug Nazivin Sensitive - up to 12 hours.
Pharmacokinetics
T1 / 2 oxymetazoline with its intranasal administration is 35 hours. Excretion in the urine is 2.1%, with feces - about 1.1%.
Indications
- colds or viral infections of the upper respiratory tract, accompanied by a runny nose, sinusitis, eustachitis, otitis media, rhinitis of any etiology; - to eliminate edema before diagnostic manipulations in the nasal passages.
Contraindications
Atrophic rhinitis; angle-closure glaucoma; hypersensitivity to the components of the drug. For Nazivin Sensitivity spray nasal dosage of 11.25 mcg / dose - children under 1 year of age. For Nazivin Sensitivity spray nasal dosage of 22.5 mcg / dose - children under 6 years of age.
Precautionary measures
Do not exceed the recommended dose. With caution, you should use the drug with elevated intraocular pressure, chronic heart failure, hypertension, angina pectoris, arrhythmia, chronic renal failure, in patients with prostatic hyperplasia with clinical symptoms (urinary retention), marked atherosclerosis, hyperthyroidism, diabetes mellitus, pheochromocytoma, as well as in patients who received MAO inhibitors during the previous 2 weeks and within 2 weeks after their cancellation, tricyclic All antidepressants, bromocriptine.
Use during pregnancy and lactation
When used during pregnancy or breastfeeding, the recommended dose should not be exceeded. The drug can be used only in those cases where the potential benefit to the mother outweighs the potential risk to the fetus or infant.
Dosage and administration
Nazivin Sensitive spray nasal dosage of 11.25 mcg / dose and 22.5 mcg / dose is intended for intranasal administration. Children aged 1 to 6 years: 1 injection Nazivin Sensitive spray nasal dosage of 11.25 mcg / dose in each nostril 2-3 times a day. The drug is used for 5-7 days. The drug is prescribed only after several days. Adults and children over 6 years old: 1 injection Nazivin Sensitive spray nasal dosage 22.5 mcg / dose into each nostril 2-3 times a day. If the symptoms worsen or the improvement does not occur within 3 days, you should consult with your doctor. At the recommended dose without consultation with a doctor, use no more than 7 days. Doses above recommended can be used only under medical supervision. One 45 mcl injection contains; - 11.25 mcg oxymetazoline hydrochloride - for Nazivin Sensitivity spray nasal dosage 11.25 mcg / dose; - 22.5 mcg oxymetazoline hydrochloride - for Nazivin Sensitivity spray nasal dosage 22.5 mcg / dose.
Side effects
Sometimes: burning or dryness of the nasal mucosa, sneezing. In rare cases: after the effect of the use of Nazivin Sensitiv, a strong feeling of nasal congestion (reactive hyperemia) will pass. Rarely: high blood pressure, headache, dizziness, heartbeat, tachycardia, anxiety, irritability, sleep disturbance ( in children), nausea, insomnia, rash, visual impairment (eye contact). Prolonged continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy of the nasal mucosa and recurrent edema of the nasal mucosa (rhinitis medication).
Overdose
Symptoms: nausea, increased blood pressure, tachycardia, CNS depression. Treatment: symptomatic therapy.
Interaction with other drugs
The drug slows down the absorption of local anesthetic drugs,lengthens their action. With the use of the drug Nazivin Sensitiv for 2 weeks before the appointment of MAO inhibitors and for 2 weeks after their withdrawal, during treatment with tricyclic antidepressants or other drugs that increase blood pressure, an increase in blood pressure is observed. risk of side effects.
special instructions
Contact with the drug should be avoided. In order to avoid the spread of infection, it is necessary to use the drug individually. Effects on the ability to drive vehicles and control mechanisms CNS. In these cases, patients should be careful when driving and engaging in other potentially hazardous activities that require increased concentration and psychomotor speed.