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Active ingredients
Composition
1 tablet contains: active ingredient: trimebutin maleate 100 mg; excipients: lactose monohydrate 81.6 mg, corn starch 32 mg, colloidal silicon dioxide (Aerosil) 3.2 mg, magnesium stearate 3.2 mg.
Pharmacological effect
Antispasmodic.
Indications
- irritable bowel syndrome;
- postoperative paralytic intestinal obstruction.
Contraindications
- children's age up to 3 years (for this dosage form);
- pregnancy;
- Lactase deficiency, glucose-galactose malabsorption;
- Hypersensitivity to trimebutine maleate and other components of the drug.
Dosage and administration
The drug is taken orally before meals.
Adults and children over 12 years old are prescribed 100-200 mg 3 times / day.
To prevent the recurrence of irritable bowel syndrome after a course of treatment during remission, it is recommended to continue taking the drug at a dose of 300 mg / day for 12 weeks.
Children at the age of 5-12 years old are prescribed 50 mg 3 times / day, children aged 3-5 years old - 25 mg 3 times / day.
Side effects
On the part of the digestive system: dry mouth, unpleasant taste, diarrhea, dyspepsia, nausea, constipation.
Nervous system disorders: drowsiness, fatigue, dizziness, anxiety, feeling hot or cold.
Allergic reactions: skin rash.
Other: menstrual disorders, painful enlargement of the mammary glands, urinary retention.
Overdose
To date, cases of overdose of trimebutin have been reported.
Interaction with other drugs
Drug interaction of the drug is not described.
special instructions
The course of treatment of irritable bowel syndrome in the acute period at a dose of 600 mg / day for 4 weeks and continued treatment after the course at a dose of 300 mg / day for 12 weeks avoids the relapse of the disease.
Influence on ability to drive motor transport and control mechanisms
The drug does not have a sedative effect, does not affect the speed of psychomotor reactions and can be used in people of various professions, including requiring increased attention and coordination of movements. However, given the possible side effects that may affect these abilities (and others), caution should be exercised when driving and doing other potentially dangerous activities.