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Active ingredients
Nicotinoyl gamma-aminobutyric acid
Release form
Pills
Composition
Active ingredient: Nicotinoyl gamma-aminobutyric acid. Concentration of active ingredient (mg): 50 mg
Pharmacological effect
Nootropic agent, dilates the blood vessels of the brain. It also has a tranquilizing, psychostimulant, antiplatelet and antioxidant effects. Improves the functional state of the brain due to the normalization of tissue metabolism and effects on cerebral circulation (increases the volumetric and linear speed of cerebral blood flow, reduces the resistance of cerebral vessels, suppresses platelet aggregation, improves microcirculation). memory, normalizes sleep; helps to reduce or eliminate feelings of anxiety, tension, fear; improves the condition of patients with motor and speech disorders.
Pharmacokinetics
Absorption is fast and complete, regardless of the route of administration. It penetrates the BBB and is retained for a long time in the tissues of the body. Bioavailability - 50-88%. Excreted mainly by the kidneys in unchanged form. T1 / 2 - 0.51 hour
Indications
Picamilon (in adults) is used in cases of mild to moderate cerebral circulation disorders, in vegetative dystonia, in anxiety, fear, irritability, abstinence (a condition resulting from a sudden cessation of alcohol intake) in patients with alcoholism, as well as to increase stability to physical and mental stress. Use the drug alone or in combination therapy.
Contraindications
The drug is contraindicated in case of individual intolerance, acute and chronic kidney diseases.
Precautionary measures
Do not exceed recommended doses.
Use during pregnancy and lactation
Contraindicated use during pregnancy, during lactation (breastfeeding).
Dosage and administration
Assign inside regardless of the meal. In cerebrovascular diseases (vascular diseases of the brain) a single dose ranges from 0.02 to 0.05 g 2-3 times a day, daily - 0.06-0.15 g. The course of treatment is 1-2 months. Repeated course after 5-6 months is recommended.In the complex therapy of depressive conditions (state of depression) in the elderly, picamilon is prescribed in daily doses of 0.04-0.2 g (2-3 doses) for 1.5-3 months. When alcoholism in the period of abstinence prescribed in doses of 0.1-0.15 g per day in a short course - 6-7 days; with more persistent violations outside of abstinence, in a daily dose of 0.04-0.06 g for 4-5 weeks. To restore health and at increased loads, picamilon is prescribed in a daily dose of 0.06-0.08 g for 1-1.5 months.
Side effects
When using picamilon, increased irritability, agitation, anxiety, dizziness, headache, mild nausea, allergic rash, itchy skin are possible. In this case, the dose should be reduced or discontinued.
Overdose
Currently, no cases of overdose have been reported.
Interaction with other drugs
Reduces the duration of the action of barbiturates. Amplifies the effect of narcotic analgesics.
special instructions
No data.