Polysorb MP powder for the preparation of suspensions for oral administration of 3 g
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Active ingredients
Colloidal silicon dioxide
Composition
1 can of colloidal silicon dioxide 12 g
Pharmacological effect
Polysorb MP is an inorganic non-selective polyfunctional enterosorbent based on highly dispersed silica with particle sizes up to 0.09 mm and with the chemical formula SiO2. Polysorb MP has pronounced sorption and detoxification properties. In the lumen of the gastrointestinal tract, the drug binds and removes from the body endogenous and exogenous toxic substances of various nature, including pathogenic bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, heavy metal salts, radionuclides, and alcohol. Polysorb MP also absorbs some metabolic products of the body, including an excess of bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis.
Pharmacokinetics
After taking the drug Polysorb MP inside the active substance is not broken down and is not absorbed in the gastrointestinal tract. Excreted from the body unchanged. Until
Indications
- acute and chronic intoxications of various etiologies in children and adults - acute intestinal infections of various etiologies, including foodborne infections, as well as diarrheal syndrome of non-infectious origin, dysbacteriosis (as part of complex therapy) - purulent-septic diseases accompanied by severe intoxication - acute poisoning with potent and poisonous substances, including drugs and alcohol, alkaloids, heavy metal salts - food and drug allergies - hyperbilirubinemia (viral hepatitis and other jaundice) and hyperasotemia (chronic renal failure) - to residents of environmentally unfriendly regions and workers in hazardous industries for the purpose of prevention.
Contraindications
- gastric ulcer and duodenal ulcer in the acute phase - gastrointestinal bleeding - intestinal atony - individual intolerance to the drug.
Use during pregnancy and lactation
Purpose of the drug Polysorb MP during pregnancy does not adversely affect the fetus. Perhaps the use of the drug Polysorb MP during pregnancy and lactation according to the indications and in the recommended doses.
Dosage and administration
Polysorb MP is ingested only in the form of an aqueous suspension.To obtain a suspension, the required amount of the drug is thoroughly stirred in 1 / 4-1 / 2 cup of water. It is recommended to prepare a fresh suspension before each drug intake and drink it 1 hour before meals or other medications. Adults drug Polysorb MP is prescribed in an average daily dose of 0.1-0.2 g / kg body weight (6-12 g). The multiplicity of reception - 3-4 times / day. The maximum daily dose in adults is 0.33 g / kg body weight (20 g). A single dose of the drug Polysorb MP for children depends on body weight (see table). Daily dose = single dose × 3 times per day. Table of recommended doses of the drug Polysorb MP. Patient's body weight Dose Water volume up to 10 kg 0.5 tsp 30-50 ml 11-20 kg 1 tsp "without slides" for 1 dose 30-50 ml 21-30 kg 1 tsp with a slide for 1 reception 50- 70 ml 31-40 kg 2 teaspoons "with a hill" for 1 reception 70-100 ml 41-60 kg 1 tablespoon "with a hill" for 1 reception 100 ml more than 60 kg 1-2 tablespoons "with a hill" for 1 intake of 100-150 ml 1 tsp "with a slide" - 1 g of the drug. 1 tablespoon "with a hill" - 2.5-3 g of the drug. In case of food allergies, the drug should be taken immediately before a meal. The daily dose is divided into 3 doses during the day. The duration of treatment depends on the diagnosis and the severity of the disease. The course of treatment for acute intoxication is 3-5 days; with allergic diseases and chronic intoxications - up to 10-14 days. After 2-3 weeks it is possible to repeat the course of treatment. Features of the use of the drug Polysorb MP in various diseases and conditions During food toxicoinfection and acute poisoning, therapy is recommended to start with gastric lavage with 0.5-1% suspension of the drug Polysorb MP. In severe poisoning on the first day, gastric lavage is carried out through a tube every 4-6 hours, along with this, the drug is given orally. A single dose for adults is 0.1-0.15 g / kg of body weight of the patient 2-3 times / day. In acute intestinal infections, treatment with Polysorb MP is recommended to begin in the first hours or days of the disease as part of complex therapy. On the first day, the daily dose of the drug is taken for 5 hours with an interval between doses of 1 hour. On the second day, the frequency of taking the drug is 4 times / day. Duration of treatment is 3-5 days. In the treatment of viral hepatitis Polysorb MP is used as a detoxification agent in an average daily dose during the first 7-10 days of illness. In case of acute allergic reactions (medicinal or food), it is recommended to prewash the stomach and intestines with a 0.5-1% suspension of the drug Polysorb MP. Further, the drug is prescribed in usual doses before the onset of clinical effect.In chronic food allergies, courses of therapy with Polysorb MP are recommended for a period of 7-10-15 days. The drug is taken immediately before meals. Similar courses are prescribed for acute recurrent urticaria, angioedema, eosinophilia, pollinosis and other atopic diseases. In chronic renal failure, the courses of treatment with the drug Polysorb MP at a dose of 0.1-0.2 g / kg / day for 25-30 days with a break of 2-3 weeks are used.
Side effects
Rarely: allergic reactions, constipation.
Overdose
Currently, data on overdose Polysorb MP is not available.
Interaction with other drugs
With the simultaneous use of the drug Polysorb MP with other drugs may reduce the therapeutic effect of the latter.
special instructions
With long-term use of the drug Polysorb MP (more than 14 days), there may be a violation of the absorption of vitamins and calcium, and therefore it is recommended that prophylactic administration of multivitamin preparations and preparations containing calcium. External powder of the drug Polysorb MP can be used in the complex treatment of purulent wounds, trophic ulcers and burns.