Resleep pills 15 mg 30 pcs
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Active ingredients
Doxylamine
Release form
Pills
Composition
1 tablet contains: Active ingredient: doxylamine succinate 15 mg.
Pharmacological effect
The blocker of histamine H1-receptors from the group of ethanolamines. It has a sedative, hypnotic effect. It reduces the time of falling asleep, increases the duration and quality of sleep, does not change the phase of sleep. It has antiallergic effect. It has m-anticholinergic activity. The severity of the sedative effect is comparable to barbiturates. Duration of action - 6-8 hours.
Pharmacokinetics
After ingestion, Cmax in the blood plasma is reached in 2-3 hours. T1 / 2 is about 10 hours.
Indications
Sleep disorders, insomnia. Allergic reactions, pruritus. As a component of the combined drugs used for colds, cough.
Contraindications
Angle-closure glaucoma, benign prostatic hyperplasia, urinary retention, lactation period, children under 6 years old (as an antihistamine), children and adolescents under 15 years (as a sedative-hypnotic), hypersensitivity to doxylamine.
Use during pregnancy and lactation
Contraindicated during lactation.
Dosage and administration
Accept Inside. Adults with insomnia, sleep disorders - 15-25 mg 15-30 minutes before sleep. In case of allergic reactions, in doses up to 25 mg every 4-6 hours. For children aged 6-12 years, 6.25-12.5 mg, if necessary, every 4-6 hours. The maximum daily dose for adults is 150 mg.
Side effects
On the part of the nervous system, daytime sleepiness (in this case, the dose of the drug should be reduced), confusion, hallucinations. On the gastrointestinal tract, constipation, dry mouth. On the side of the cardiovascular system, a sensation of heartbeat. accommodation, blurred vision. From the urinary system, urinary retention. From the laboratory indicators an increase in creatine phosphokinase levels. From the side of the musculoskeletal system rhabdomyolysis, if any of these In the instructions, adverse reactions are aggravated, or you notice any other undesirable effects that are not listed in the instructions, inform your doctor.
Interaction with other drugs
With simultaneous use with antidepressants, barbiturates, benzodiazepines, clonidine, opioid analgesics, neuroleptics, tranquilizers, the inhibitory effect of doxylamine on the central nervous system is enhanced. When used simultaneously with atropine and atropine-like agents, imipramine, anti-Parkinsonian drugs with anticholinergic action, disopyramide, phenothiazine derivatives, the risk of anticholinergic side effects (dry mouth, constipation, urinary retention) increases. When applied simultaneously with ethanol, the sedative effect of doxylamine is enhanced.
special instructions
It is used with caution in lung diseases. Impact on the ability to drive motor vehicles and control mechanisms: When doxylamine is treated (mainly when applied during the daytime - in allergic reactions, itching, as part of combination preparations for treating colds), it is necessary to avoid driving vehicles as well as other activities that require fast psychomotor reactions.