Riboxin coated pills 200mg N50
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Active ingredients
Inosine
Release form
Pills
Composition
Active ingredient: Inosine (Inosine) Active ingredient concentration (mg): 200
Pharmacological effect
Purine nucleoside, the precursor of ATP. It improves myocardial metabolism, has antihypoxic and antiarrhythmic effect. Increases the energy balance of the myocardium. It has a protective effect on the kidneys in conditions of ischemia during surgery. It participates in the exchange of glucose, increases the activity of a number of Krebs cycle enzymes. Stimulates nucleotide synthesis.
Pharmacokinetics
Inosine is well absorbed from the gastrointestinal tract. Metabolized in the liver with the formation of glucuronic acid and its subsequent oxidation. In small quantities excreted by the kidneys.
Indications
Prescribed to adults in the treatment of ischemic heart disease, myocardial dystrophy, after myocardial infarction, cardiac rhythm disturbances caused by the use of cardiac glycosides. Appoint with hepatitis, cirrhosis, fatty liver caused by alcohol or drugs and uro-proporphyria.
Contraindications
Hypersensitivity to the components of the drug, gout, hyperuricemia. Pregnancy and lactation, children under 18 years.
Precautionary measures
With the development of allergic reactions necessary to cancel the drug.
Use during pregnancy and lactation
Category of action on the fetus by the FDA - not determined.
Dosage and administration
Assign inside to food. The daily dose for oral administration is 0.6-2.4 g. In the first days of treatment, the daily dose is 0.6-0.8 g (0.2 g 3-4 times a day). In case of good tolerance, the dose is increased by 1.2 g (0.4 g 3 times a day), if necessary, to 2.4 g per day. The course duration is from 4 weeks to 1.5-3 months.
Side effects
Allergic reactions in the form of urticaria, pruritus, flushing of the skin are possible. Rarely, drug treatment increases the concentration of uric acid in the blood and exacerbation of gout.
Overdose
Possible individual intolerance of the drug in the form of itching, skin hyperemia (the drug is canceled and desensitization therapy is carried out).
Interaction with other drugs
With the simultaneous use of Riboxin with β-adrenoreceptor blockers, the effect of Riboxin is not reduced.When combined with cardiac glycosides, the drug can prevent the occurrence of arrhythmias and enhance the inotropic effect. Riboxin should not be mixed in the same syringe with other drugs to avoid chemical incompatibility of drugs.
special instructions
Caution is prescribed inosine for renal dysfunction.