Rozamet cream for external use of 25 g
Condition: New product
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Active ingredients
Metronidazole
Release form
Cream
Composition
Active ingredient: Metronidazole (Metronidazolum) Active ingredient concentration (mg): 10
Pharmacological effect
When applied topically, it has an anti-acne effect, the mechanism of which is unknown (not related to the effect on the tick demodex folliculorum found in the hair follicles and secretion of the sebaceous glands, and any influence on the production of this secret). metronidazole for external use may have antioxidant activity. It was found that it significantly reduces the production of active oxygen by neutrophils, hydroxyl radicals and hydrogen peroxide, which are potential oxidants that can cause tissue damage at the site of inflammation. metronidazole for external use is ineffective against telangiectasia, marked with pink acne.
Pharmacokinetics
When applied topically, the drug is practically not absorbed.
Indications
Inflamed papules, pustules; - erythema with pink and acne vulgaris (acne rozacea, acne vulgaris); - balanoposthitis; - vulvovaginitis.
Contraindications
Hypersensitivity.
Precautionary measures
Keep the temperature not exceeding 25 ° C, out of the reach of children.
Use during pregnancy and lactation
With care: pregnancy (I trimester), lactation.
Dosage and administration
Outwardly. Treatment of inflamed papules, pustules, erythema in case of pink and acne vulgaris (acnerozacea, acnevulgaris): applied to the skin previously cleaned with warm water or light detergent and thin 1-2 times a day, in the morning and in the evening. The course of treatment for 1-2 months. Between cleansing the skin and applying the cream is recommended to take a break of 15-20 minutes. The therapeutic effect occurs after about 3 weeks. The average duration of treatment is 3-4 months. Balanoposthitis, vulvovaginitis: squeezing out a small amount of cream from a tube, is applied to the surface of lesions of the glans head, foreskin, the region of the labia minora, vagina vestibule, using a cotton swab or fingers, lightly rubbing 1-2 times a day. Duration of treatment is 8-10 days.
Side effects
Side effects after external use of metronidazole are extremely rare.Allergic reactions are possible (urticaria, skin rash); hyperemia, peeling and burning of the skin, watery eyes.
Overdose
Data on cases of overdose when applied topically is not available.
Interaction with other drugs
After external use, the concentration of metronidazole is very low and the possibility of interaction is minimal. With simultaneous appointment enhances the effect of warfarin and other indirect anticoagulants.
special instructions
The drug is intended for external use only. Avoid contact with eyes, as this can cause eye inflammation and tearing. In case of contact with eyes, wash them with plenty of water. In case of skin inflammation, the frequency of use of the drug should be reduced or temporarily discontinued. During the use of the drug should avoid direct sunlight.