Rutacid Chewable Tablets 60 pcs
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Active ingredients
Hydrotalcite
Release form
Pills
Composition
1 chewable tablet contains: hydrotalcite 500 mg. Excipients: mannitol, sodium saccharin, spikelet mint, sodium starch aglycolate, talc, magnesium stearate.
Pharmacological effect
Hydrotalcite has a layered-mesh structure with a low content of aluminum and magnesium. The release of aluminum ions and magnesium occurs gradually, depending on the pH of the gastric juice. The drug provides a quick and long-lasting neutralization of hydrochloric acid with maintaining the pH close to normal levels. It has a protective effect on the gastric mucosa. Reduces the proteolytic activity of pepsin, binds bile acids.
Pharmacokinetics
The release of magnesium and aluminum ions occurs gradually in the stomach, depending on the pH value. Hydrotalcite is absorbed in the small intestine. After ingestion, the content of magnesium and aluminum ions in the blood plasma is temporarily increased, but penetration into the nervous and bone tissues does not occur (with normal kidney function). The absorbed part is excreted by the kidneys.
Indications
Acute gastritis. Chronic gastritis with increased secretory function in the acute phase. Acute and chronic duodenitis. Peptic ulcer and duodenal ulcer. Reflux esophagitis. Discomfort and pain in the epigastrium, heartburn, sour belching after errors in the diet, excessive alcohol consumption, medication.
Contraindications
Renal failure. Hypersensitivity to hydrotalcite and other components of the drug.
Precautionary measures
With care: chronic renal failure, hypophosphatemia.
Use during pregnancy and lactation
There is no confirmed evidence of undesirable effects of hydrotalcite during pregnancy and breastfeeding. Use of the drug Rutacid during pregnancy is allowed if the potential benefit to the mother outweighs the possible risk to the fetus. The drug Rutacid does not penetrate into breast milk, so its use is possible during breastfeeding.
Dosage and administration
Adults appoint 500-1000 mg (1-2 pills) 3-4 times / day 1 h after a meal and before bedtime.For discomfort and pain in epigastria, heartburn, sour belching after errors in diet, drinking alcohol, taking drugs -1000 mg (1-2 pills) once. Children aged 6–12 years old should be given half the dose for adults. The duration of treatment is determined individually. Tablets should be chewed thoroughly.
Side effects
On the part of the digestive system when taking the drug in high doses possible diarrhea.
Overdose
No signs of intoxication due to drug overdose have been reported.
Interaction with other drugs
Like other antacids, Rutacid can reduce the absorption of tetracyclines, quinolones (ciprofloxacin, ofloxacin), iron preparations and coumarins, antibiotics.
special instructions
The interval between the use of the drug Rutacid and other medicines should be at least 1-2 hours. It is not recommended to use the drug Rutacid simultaneously with acidic beverages (juices, wine). Rutacid does not contain sucrose, so it can be taken by patients with diabetes. Polyols (mannitol) can cause diarrhea. Impact on the ability to drive vehicles and control mechanisms: The drug Rutacid does not affect the ability to drive vehicles and other complex technical devices that require concentration of attention and speed of psychomotor reactions.