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Active ingredients
Sennosides a and b
Release form
Pills
Composition
1 tablet contains: Active ingredient: leaf senna extract 93.33 mg (containing the sum of calcium salts of sennozid A and B in terms of sennoside B - 13.5 mg); ; Excipients: lactose - 23.07 mg, starch - 43.56 mg, methyl parahydroxybenzoate - 0.04 mg, microcrystalline cellulose - 15.0 mg, talc - 11.13 mg, magnesium stearate - 0.93 mg, sodium lauryl sulfate - 0.93 mg, carmellose sodium - 2.00 mg.
Pharmacological effect
It has a laxative effect, occurring after 8-10 hours. The laxative effect is due to the effect on the receptors of the large intestine, which increases peristalsis.
Indications
Constipation caused by hypotension and sluggish peristalsis of the large intestine. Regulation of the chair with hemorrhoids, proctitis, anal fissures.
Contraindications
Hypersensitivity to the drug components Senade; spastic constipation; intestinal obstruction; abdominal pain of obscure origin; strangulated hernia,; acute inflammatory diseases of the abdominal cavity; peritonitis,; gastrointestinal and uterine bleeding; cystitis,; violations of water and electrolyte metabolism .;
Use during pregnancy and lactation
It should not be taken during pregnancy (effectiveness and safety are not well understood) .; At the time of treatment, breastfeeding is recommended to stop. The active ingredients can penetrate into breast milk and cause frequent, loose stools in the infant.
Dosage and administration
Senade is taken internally, usually 1 time per day in the evening before bedtime, drinking water or some kind of drink .; Adults and children over 12 years old: 1 tablet per reception. In the absence of effect, the dose can be increased to 2-3 pills .; Children 6-12 years old: 1/2 tablet and, if necessary, increase the dose to 1-2 pills .; In the process of selecting the same dose should be taken over several days and gradually increase it by 1/2 tablet. If, after reaching the maximum dose within 3 days, the defecation does not occur, it is necessary to consult a doctor.
Side effects
The laxative effect of the drug may be accompanied by colicky abdominal pain, flatulence. With prolonged use, especially in high doses, possible violations of water-electrolyte metabolism, albuminuria, hematuria, deposition of melanin in the intestinal mucosa, nausea, vomiting, diarrhea, urine discoloration, skin rash, convulsions, vascular collapse, fatigue, confusion.
Overdose
Symptoms: The main adverse effect in overdose is diarrhea leading to dehydration .; Treatment: conservative measures - increase fluid intake. This is usually enough to compensate for the loss of fluid and electrolytes. In some cases, it is necessary to compensate for the loss of fluid and electrolytes with the help of IV infusion of plasma substitutes.
Interaction with other drugs
With prolonged use of Senad in high doses, it is possible to enhance the action of cardiac glycosides and the effect on the action of antiarrhythmic drugs in connection with the possibility of the development of hypokalemia .; With simultaneous use with thiazide diuretics, glucocorticoids, licorice root preparations increases the risk of hypokalemia.
special instructions
It is not recommended to use the drug for more than 2 weeks .; After taking the drug, the urine may acquire a yellow-brown or red-lilac color.