Slabilen coated pills 5mg N20
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Active ingredients
Sodium picosulphate
Release form
Pills
Composition
Sodium picosulfate 5 mg Auxiliary substances: potato starch 27.64 mg, lactose monohydrate 58.45 mg, povidone 2.96 mg, magnesium stearate 0.95 mg. Film coating composition: Opadry II yellow 2.85 mg, including polyvinyl alcohol 1.14 mg, talc 0.422 mg, macrogol 0.576 mg, titanium dioxide 0.695 mg, iron dye yellow oxide 0.017 mg.
Pharmacological effect
Laxative. Under the action of intestinal microorganisms, it is hydrolyzed to form an active form, which causes irritation of the receptors of the intestinal mucosa and enhancement of its motility.
Pharmacokinetics
After ingestion is not absorbed from the gastrointestinal tract and is not subjected to hepato-intestinal circulation.
Indications
Constipation due to hypotension and a sluggish peristalsis of the colon. Regulation of the chair with hemorrhoids, proctitis, anal fissures. Preparation for surgery, instrumental and radiological studies.
Contraindications
Intestinal obstruction, restrained hernia, acute inflammatory diseases of the abdominal organs, peritonitis, abdominal pain of unknown origin, gastrointestinal bleeding, uterine bleeding, cystitis, spastic constipation, children under 4 years old, I trimester of pregnancy, severe dehydration, hypersensitivity to sodium picosulphate.
Use during pregnancy and lactation
Contraindicated in the first trimester of pregnancy. Apply in the II and III trimester of pregnancy should be only if the intended benefits to the mother outweigh the possible risk to the fetus. If necessary, use during lactation should stop breastfeeding.
Dosage and administration
Individual, depending on the age and patient response to treatment. Take inside before bedtime.
Side effects
Possible: diarrhea, which can lead to excessive loss of fluid and electrolytes, the appearance of weakness, seizures, hypotension, abdominal pain.
Interaction with other drugs
With simultaneous use with broad-spectrum antibiotics, it is possible to reduce the laxative effect of sodium picosulfate. With simultaneous use with diuretics, with GCS may increase the risk of electrolyte disorders.An electrolyte imbalance that occurs when high doses of sodium picosulphate are taken can lead to a deterioration in the tolerability of cardiac glycosides when used simultaneously.
special instructions
It has no taste, so children can be added to food. Do not use daily without medical supervision for more than 10 days.