Sulfacyl sodium drops eye tube-drops 20% 1.5 ml N2
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Active ingredients
Sulfacetamide
Release form
Drops
Composition
1 ml of drops contains: Active ingredient: sulfacetamide 200 mg. Excipients: sodium thiosulfate - 1 mg, hydrochloric acid 1 M - to pH 7.5-8.7, purified water - to 1 ml.
Pharmacological effect
Antibacterial agent for local use in ophthalmology, sulfanilamide derivative. It has a wide spectrum of antimicrobial action. It has a bacteriostatic effect. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to disruption of the synthesis of tetrahydrofolic acid, necessary for the synthesis of purines and pyrimidines. Sulphacetamide is active against gram-positive and gram-negative bacteria (including pathogenic cocci, Escherichia coli), Chlamydia spp., Actinomyces spp.
Pharmacokinetics
When applied topically penetrates the tissues and eye fluids. It is absorbed into the systemic circulation through the inflamed conjunctiva.
Indications
Purulent corneal ulcers, conjunctivitis, blepharitis, gonorrheal eye diseases in newborns and adults, prevention of necrosis in newborns.
Contraindications
Hypersensitivity to sulfacetamide and other sulfanilamide drugs.
Dosage and administration
Apply 2-3 drops to the lower conjunctival sac of each eye 5-6 times / day. To prevent blistering in newborns, 2 drops of the solution are instilled into the eyes immediately after birth and 2 drops after 2 hours.
Side effects
Local reactions: itching, redness, swelling.
Overdose
Data on drug overdose are not available. In case of contact with an excessive amount of the drug, it is recommended to wash the eyes with warm water.
Interaction with other drugs
When applied locally, sulfacetamide is incompatible with silver salts.
special instructions
Patients with hypersensitivity to furosemide, thiazide diuretics, sulfonylurea, or carbonic anhydrase inhibitors may be hypersensitive to sulfacetamide.