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Active ingredients
Troxerutin
Release form
Gel
Composition
In 1 g of gel: troxerutin 20 mg. Excipients: carbomer - 6 mg, trolamine (triethanolamine) - 7 mg, disodium edetate dihydrate - 0.5 mg, benzalkonium chloride - 1 mg, purified water - 965.5 mg.
Pharmacological effect
Troxevasin; is a flavonoid (derivative of rutin). Possesses P-vitamin activity; has a venotonic, venoprotective, anti-edema, anti-inflammatory, anti-clotting and antioxidant action. Reduces permeability and fragility of capillaries, increases their tone. Increases the density of the vascular wall, reduces the exudation of the liquid part of the plasma and the diapedesis of the blood cells. Reduces inflammation in the vascular wall, limiting the adherence of platelets to its surface.
Pharmacokinetics
When applying the gel on the affected area, the active substance quickly penetrates the epidermis, after 30 minutes it is found in the dermis, and after 2-5 hours in the subcutaneous fatty tissue.
Indications
Varicose veins; chronic venous insufficiency with symptoms such as: swelling and pain in the legs; feeling of heaviness, fatigue, tired legs; spider veins and spider veins, convulsions, paresthesias; thrombophlebitis; periflebitis; varicose dermatitis; traumatic pain and swelling (bruises, sprains, injuries).
Contraindications
Violation of the integrity of the skin; hypersensitivity to the drug.
Precautionary measures
Avoid contact with open wounds, eyes and mucous membranes.
Use during pregnancy and lactation
Use during pregnancy and breastfeeding There are no data on undesirable effects on the fetus and newborn when using the drug.
Dosage and administration
Outwardly. The gel is applied to the affected area 2 times / day in the morning and evening, gently rubbing until completely absorbed. If necessary, the gel can be applied under bandages or elastic stockings. The success of drug treatment largely depends on its regular use for a long time. It is recommended to combine with taking Troxevasin capsules; to enhance exposure. If the symptoms of the disease worsen or do not disappear after 6-7 days of daily use of the drug, the patient should consult a doctor.
Side effects
In rare cases, allergic skin reactions are observed - urticaria, eczema, dermatitis.
Overdose
Due to the external method of application and the large therapeutic breadth of the drug there is no danger of overdose. If a large amount of gel is accidentally swallowed, general measures should be taken to expel the drug from the body (emetics) and consult a doctor. If indicated, peritoneal dialysis is performed.
Interaction with other drugs
Currently, data on drug interactions drug Troxevasin; are missing.
special instructions
The gel is applied only on an intact surface. In conditions characterized by increased vascular permeability (including scarlet fever, influenza, measles, allergic reactions), the gel is used in combination with ascorbic acid to enhance its effect. The effect on the ability to drive motor vehicles and the management of the mechanisms of Troxevasin; gel does not affect the ability to drive a motor vehicle and work with moving machinery.