Zalain vaginal suppositories 300mg N1
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Active ingredients
Sertaconazole
Release form
Suppositories
Composition
Sertaconazole nitrate 300 mg. Adjuvants: Witepsol - 1.305 g, suppocyr - 1.305 g, silica colloid anhydrous - 0.09 g.
Pharmacological effect
Antifungal drug, a derivative of imidazole and benzothiophene. In therapeutic doses has fungistatic and fungicidal action. The mechanism of action is to suppress the synthesis of ergosterol and increase the permeability of the cell membrane, which leads to the lysis of the cell of the fungus. It is active against Candida spp. It also has antibacterial activity against gram-positive bacteria (Streptococcus spp., Staphylococcus spp.).
Pharmacokinetics
With intravaginal use of the drug is not absorbed.
Indications
Local treatment of infections of the mucous membrane of the vagina, caused by fungi of the genus Candida (vulvovaginal candidiasis).
Contraindications
Hypersensitivity to imidazole derivatives, benzofithen and other components of the drug.
Precautionary measures
With simultaneous infection of the labia and adjacent areas (candidal vulvitis), local treatment with Zalain should be further carried out; cream.
Use during pregnancy and lactation
There are no sufficient data on the use of Zalain during pregnancy and lactation. Taking into account the method of use of the drug (single injection), as well as the lack of systemic absorption, the use of Zalain during pregnancy and lactation is possible if the intended benefit to the mother outweighs the possible risk for fetus or baby.
Dosage and administration
The drug is used once. 1 vaginal suppository is inserted deep into the vagina, lying on his back, before bedtime. In case of preservation of clinical symptoms, it is possible to re-use the drug after 7 days. Before using the drug, you should wash the external genitals with neutral or alkaline soap.
Side effects
Rarely: burning sensation, itching in the vagina, which pass independently during treatment and do not require discontinuation of the drug. These side effects are classic for topical preparations and reflect the effectiveness of the drug. It is possible: allergic reactions.
Overdose
Not installed. When accidentally taking the drug inside, you must flush the stomach and immediately consult a doctor.
Interaction with other drugs
With simultaneous use of the drug Zalain; with local contraceptives may be a weakening of the spermicidal action of the latter.
special instructions
Treatment can be carried out during menstruation. When using the drug, it is recommended to refrain from sexual intercourse. To prevent urogenital reinfection, it is recommended to consider the simultaneous treatment of the sexual partner. The risk of damage to barrier contraceptives (condom or diaphragm rupture) increases with their simultaneous use with Zalain. ability to drive vehicles and control mechanismsApplication Zalain does not affect the ability to perform potentially op waist activities requiring high concentration and psychomotor speed (including the driving vehicles).