Amelotex gel for nar.primen.1% 50g
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Active ingredients
Meloxicam
Release form
Gel
Composition
100 g meloxicam (in terms of 100% substance) 1 g. Excipients: sodium metabisulfite - 0.4 mg, water d / and - up to 1 ml.
Pharmacological effect
NSAIDs for external use. It has analgesic, anti-inflammatory action. Anti-inflammatory effect is associated with inhibition of the enzymatic activity of COX-2, which is involved in the biosynthesis of prostaglandins in the area of inflammation. To a lesser extent, meloxicam acts on COX-1, which is involved in the synthesis of prostaglandin, which protects the gastrointestinal mucosa and is involved in the regulation of blood flow in the kidneys. Meloxicam is a chondron-neutral drug that does not adversely affect the cartilage tissue, does not affect the synthesis of proteoglycan by articular cartilage chondrocytes. When applied locally, the drug reduces or eliminates pain in the area of application of the gel, including joint pains at rest and when moving. Contributes to increased range of motion.
Indications
- symptomatic therapy of osteoarthritis, accompanied by pain. It is used for symptomatic therapy, reducing pain and inflammation. the progression of the disease is not affected.
Contraindications
- complete or incomplete combination of asthma, recurrent nasal polyposis and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (including in history) - violation of the integrity of the skin in the areas of the intended application - children and adolescents under 18 years of age (effectiveness and safety is not established) - pregnancy - hypersensitivity to meloxicam and other components of the drug (including to other NSAIDs). The drug should be used with caution in gastric ulcer and duodenal ulcer (in acute phase) active gastrointestinal bleeding, progressive progressive kidney failure, severe or active liver disease, confirmed by hyperkalemia and inflammatory bowel disease, in case of a coagulatory heart failure, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure rate, a heart failure, a heart failure, a heart failure, a heart failure, a heart failure)
Use during pregnancy and lactation
The use of the drug is contraindicated in pregnancy and during breastfeeding.
Dosage and administration
Outwardly.Do not apply inside. A strip of gel with a length of about 4 cm (2 g) is applied 2 times / day in a thin layer on clean, dry skin over the lesion and lightly rubbed for 2-3 minutes. The duration of the course of therapy is determined individually, may vary depending on the location of the lesion and the noted therapeutic effect and is not more than 4 weeks.
Side effects
For drugs from the NSAID group for external use, the following side effects are described. On the part of the skin: hyperemia, papular-vesicular rash, peeling, photosensitization. Allergic reactions: itching and burning of the skin, erythema multiforme, urticaria, systemic anaphylactic reactions. If adverse reactions occur, incl. not listed above, the patient should stop using the gel and inform the attending physician.
special instructions
The following side effects are described for preparations from the NSAID group for external use. On the part of the skin: hyperemia, papular-vesicular rash, peeling, photosensitization. Allergic reactions: itching and burning of the skin, erythema multiforme, urticaria, systemic anaphylactic reactions. If adverse reactions occur, incl. not listed above, the patient should stop using the gel and inform the attending physician.