Calcium gluconate pills N20
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Active ingredients
Calcium gluconate
Release form
Pills
Composition
Calcium gluconate 500 mg
Pharmacological effect
Calcium is a macro element involved in the formation of bone tissue, the process of blood coagulation, is necessary to maintain stable cardiac activity, the processes of transmission of nerve impulses. Improves muscle contraction in muscular dystrophy, myasthenia, reduces vascular permeability. With the on / in the introduction of calcium causes the excitation of the sympathetic nervous system and increased release of adrenaline by the adrenal glands; has a moderate diuretic effect.
Indications
Hypocalcemia of various genesis, hypoparathyroidism, parenchymal hepatitis, toxic liver damage, nephritis, eclampsia, hyperkalemic form of paroxysmal myoplegia, inflammatory and exudative processes, skin diseases. As an additional tool in the treatment of allergic diseases and drug allergies. As an additional hemostatic agent for pulmonary, gastrointestinal, nasal, uterine bleeding. As an antidote for poisoning with magnesium salts, oxalic acid and its soluble salts.
Contraindications
Hypercalcemia, severe hypercalciuria, severe renal failure, tendency to thrombosis, hypersensitivity to calcium gluconate.
Dosage and administration
For ingestion a single dose - 1-3 g, the multiplicity of reception - 2-3 times / day. When i / v or i / m administration of calcium gluconate solution, a single dose of the drug should correspond to 2.25-4.5 mmol of calcium. Calcium chloride solution is administered intravenously in a jet (slowly) in a single dose of 500 mg, in intravenous drip in a single dose of 0.5-1 g.
Side effects
Possible: nausea, vomiting, diarrhea, bradycardia; with the / m introduction - necrosis.
Overdose
Symptoms: development of hypercalcemia. Treatment: calcitonin, intravenously at the rate of 5-10 ME / kg / day (the drug is diluted in 500 ml of 0.9% sodium chloride solution, administered by drip for 6 hours).
Interaction with other drugs
Calcium gluconate with simultaneous use reduces the effect of calcium channel blockers. In / in the introduction of calcium gluconate before or after verapamil reduces its hypotensive effect, but does not affect its antiarrhythmic effect. Under the influence of Kolestiramin calcium absorption from the gastrointestinal tract is reduced.With simultaneous use with quinidine may slow intraventricular conductivity and increase the toxicity of quinidine. During treatment with cardiac glycosides, parenteral administration of calcium gluconate is not recommended, due to increased cardiotoxicity. With simultaneous oral administration of calcium gluconate and tetracyclines, the action of the latter may decrease, due to a decrease in their absorption.
special instructions
It is used with caution in patients with a small hypercalciuria, with minor impaired renal function or with a history of urolithiasis; in these cases, urinary calcium excretion should be regularly monitored. Patients with a tendency to the formation of stones in the urine is recommended to increase the volume of fluid intake. It is not recommended to enter the / m children.