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Active ingredients
Polymethylsiloxane polyhydrate
Release form
Gel
Composition
Polymethylsiloxane polyhydrate 70 g. Additives: purified water - 30 g
Pharmacological effect
Enterosorbent, intestinal adsorbent. Enterosgel; has a porous structure of the silicone matrix (molecular sponge) of a hydrophobic nature, which is characterized by sorption action with respect to only the weight-carrying toxic metabolites (m. from 70 to 1000). Enterosgel; possesses pronounced sorption and detoxification properties. In the lumen of the gastrointestinal tract, the drug binds and removes from the body endogenous and exogenous toxic substances of various nature, including bacteria and bacterial toxins, antigens, food allergens, drugs, poisons, heavy metal salts, and alcohol. The drug also absorbs some metabolic products of the body, including an excess of bilirubin, urea, cholesterol, lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis. Enterosgel; does not reduce the absorption of vitamins and microelements, helps to restore the disturbed intestinal microflora and does not affect its motor function.
Pharmacokinetics
The drug is not absorbed from the gastrointestinal tract. Provided unchanged for 12 hours.
Indications
In adults and children as a detoxification agent: - acute and chronic intoxications of various origins — acute poisonings with potent and toxic substances (including drugs, alcohol, alkaloids, heavy metal salts) - acute intestinal infections of any origin as part of complex therapy (including toxicoinfection, salmonellosis, dysentery, diarrheal syndrome of non-infectious origin, dysbacteriosis) - purulent-septic diseases, accompanied by severe intoxication, composed of ompleksnoy terapii- food and drug allergiya- hyperbilirubinemia (viral hepatitis) - hyperasotemia (chronic renal failure) - prevention of chronic intoxications of harmful plants in workers (occupational exposure to chemical agents polytropic actions xenobiotics, incorporated radionuclides, compounds of lead, mercury, arsenic, petroleum, organic solvents, oxides of nitrogen, carbon, fluorides,salts of heavy metals). ICD-10 codes
Contraindications
- idiosyncrasy of the drug - intestinal atony.
Dosage and administration
Enterosgel; take orally 1-2 hours before or after eating or taking other medicines with water. It is recommended to mix the amount of the drug required in the reception in a glass in a threefold volume of water at room temperature or to take it inside with a glass of water. Adults - 22.5 g (1 bag or 1.5 tablespoons) 3 times / day. Daily dose - 67.5 g (3 packs). Children aged 5 to 14 years - 15 g (1 tablespoon) 3 times / day. Daily dose - 45 g (2 packets). Children under 5 years old - 7.5 g (0.5 tablespoon) 3 times / day. Daily dose - 22.5 g (1 packet). It is recommended that infants 2.5 g (0.5 teaspoonful) of the drug be mixed in triple volume of breast milk or water and given before each feeding - 6 times / day. For the prevention of chronic intoxication - 22.5 g (1 pack) 2 times / day for 7-10 days every month. For severe intoxication during the first 3 days, the dose of the drug can be doubled. The duration of treatment for acute poisoning is 3-5 days, and for chronic intoxications and allergic conditions - 2-3 weeks. Repeated course on the recommendation of a doctor.